METHODS OF TREATING ACUTE KIDNEY INJURY

1 . A method of treating a human patient with acute kidney injury comprising intravenously administering to the patient an effective amount of a compound represented by the following structural formula:

or a pharmaceutically acceptable salt thereof.

2 . The method of claim 1 , comprising intravenously administering to the patient an effective amount of the meglumine salt of the compound.

3 . A method of treating a human patient with acute kidney injury comprising administering to the patient an effective amount of a compound represented by the following structural formula:

or a pharmaceutically acceptable salt thereof.

4 . A method of treating a human patient with acute kidney injury comprising administering to the patient an effective amount of a compound represented by the following structural formula:

or a pharmaceutically acceptable salt thereof.

5 . The method of claim 3 , wherein the compound is administered intravenously.

6 . The method of claim 3 , wherein the compound is administered orally.

7 . The method of claim 1 , wherein the patient is being treated for acute kidney injury from acute interstitial nephritis.

8 . The method of claim 1 , wherein the patient is being treated for acute kidney injury from glomerular renal disease.

9 . The method of claim 1 , wherein the patient is being treated for acute kidney injury from acute vasculitic renal disease.

10 . The method of claim 1 , wherein the patient is being treated for acute kidney injury from ischemia.

11 . The method of claim 1 , wherein the patient is being treated for acute kidney injury from toxic injury.

12 . The method of claim 1 , wherein the patient is being treated for acute kidney injury from prerenal axotemia.

13 . The method of claim 1 , wherein the patient is being treated for acute kidney injury from acute postrenal destructive nephropathy.

14 . The method of claim 1 , wherein the patient the patient is being treated for acute kidney injury from diabetes, underlying renal insufficiency, nephritic syndrome, atherosclerotic disease, sepsis, hypotension, hypoxia, myoglobinuria-hematuria, or liver disease.

15 . The method of claim 1 , wherein the patient being treated for acute kidney injury or is elderly, pregnant, a surgical patient, or has been exposed to a nephrotoxic agent.

16 . The method of claim 15 , wherein the patient is a surgical patient.

17 . The method of claim 15 , wherein the patient has been exposed to a nephrotoxic agent and the nephrotixuc agent is a drug or chemical capable of causing acute kidney injury.

18 . The method of claim 17 , wherein the drug or chemical is one or more of the compounds selected from the group consisting of cisplatin; gentamicin; cephaloridine; cyclosporine; amphotericin; carbon tetrachloride; trichloroethylene; and dichloroacetylene.

19 - 24 . (canceled)

25 . The method of claim 4 , wherein the compound is administered intravenously.

26 . The method of claim 4 , wherein the compound is administered orally.