IP Library Granted Patent US 11,179,043
Granted Patent B2
US 11,179,043 · App. 16/338,290 · Granted Nov 23, 2021

Apparatus for determining a functional index for stenosis assessment

Inventors: Christian Haase (Hamburg, DE); Michael Grass (Buchholz in der Nordheide, NL); Bram Antonius Philomena Van Rens (Utrecht, NL); Roland Wilhelmus Maria Bullens (Mierlo, NL); Peter Maria Johannes Rongen (Eindhoven, NL); Arjen Van Der Horst (Tilburg, NL); Raoul Florent (Ville D'Avray, FR); Romane Isabelle Marie-Bernard Gauriau (Paris, FR); Javier Olivan Bescos (Eindhoven, NL); Holger Schmitt (Luetjensee, DE); Vincent Maurice André Auvray (Meudon, FR)
Assignee: KONINKLIJKE PHILIPS N.V.
A61B5/02007A61B5/021A61B5/026A61B5/1075A61B6/5217G06T7/62A61B5/1079G06T2207/10116G06T2207/30104
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Quick Facts
Patent No.
US 11,179,043
App. No.
16/338,290
Filed
Mar 29, 2019
Granted
Nov 23, 2021
Kind
B2
Art Unit
2662
USPC
382/132
Abstract

An apparatus for determining a functional index for stenosis assessment of a vessel is provided. The apparatus comprises an input interface ( 40 ) and a processing unit ( 50 ). The input interface is configured to obtain image data ( 30 ) representing a two-dimensional representation of a vessel ( 6 ). The processing unit ( 50 ) is configured to determine a course of the vessel ( 6 ) and a width (w 1 , w 2 ) of the vessel along its course in the image data and is further configured to determine the functional index for stenosis assessment of the vessel based on the width of the vessel in the image data.

Claims (32)

1. An apparatus for determining a functional index for stenosis assessment of a vessel, comprising:

an input interface; and

a processing unit;

wherein the input interface is configured to obtain image data corresponding to a two-dimensional representation of the vessel;

wherein the processing unit is configured to:

determine a geometric model of at least a section of the vessel based on the image data, the model including an inner diameter and a change of the inner diameter along a course of the vessel;

determine at least one resistance value of at least the section of the vessel based on the geometric model; and

determine a pressure drop of a fluid flowing through at least the section of the vessel based on:

the at least one resistance value; and

boundary conditions including a volumetric flow rate and/or a pressure associated with an inlet and/or an outlet of at least the section of the vessel,

wherein the pressure drop is an equivalent of the functional index for stenosis assessment, and

wherein the functional index is generated using a single 2D projection image.

2. The apparatus according to claim 1 , wherein the processing unit is configured to apply a densitometry method to the image data as to compensate for foreshortening effects in the image data when determining a width of the vessel.

3. The apparatus according to claim 1 , wherein the processing unit is configured to apply a scaling factor to a width of the vessel in the image and to determine the functional index for stenosis assessment based on the width multiplied by the scaling factor.

4. The apparatus according to claim 3 , wherein the processing unit is configured to receive a distance of the vessel from an image plane of the image data and to determine the scaling factor based on said distance.

5. The apparatus according to claim 3 , wherein the processing unit is configured to segment the vessel along its course such that there are multiple vessel segments and to apply a specific scaling factor to the width of each one of the multiple vessel segments.

6. The apparatus according to claim 5 , wherein the processing unit is configured to segment the vessel based on a distance between a segment of the vessel and a projection surface.

7. The apparatus according to claim 3 , wherein the processing unit is configured to detect a reference element within the image data and to determine the scaling factor based on a known size of the reference element and the size of the reference element in the image data.

8. The apparatus according to claim 1 , wherein a respective functional index for stenosis assessment is independently derived from a corresponding one of a plurality of 2D images.

9. The apparatus according to claim 8 , wherein a variation between the functional indices from different images is determined and compared to a predetermined maximal variation (Vmax), based on which an acceptance criterion is generated.

10. The apparatus according to claim 1 , wherein the processing unit is configured to calculate a quality score for one or more 2D images being used as a basis for calculating the functional index for stenosis assessment.

11. A method for determining a functional index for stenosis assessment, comprising the following steps:

obtaining image data corresponding to two-dimensional representation of a vessel;

determining a geometric model of at least a section of the vessel based on the image data, the model including an inner diameter and a change of the inner diameter along a course of the vessel;

determining at least one resistance value of at least the section of the vessel based on the geometric model; and

determining a pressure drop of a fluid flowing through at least the section of the vessel based on:

the at least one resistance value; and

boundary conditions including a volumetric flow rate and/or a pressure associated with an inlet and/or an outlet of at least the section of the vessel,

wherein the determined pressure drop is an equivalent of the functional index for stenosis assessment, and

wherein the functional index is generated using a single 2D projection image.

12. A non-transitory computer readable medium having stored thereon a computer program element adapted to control the apparatus according to claim 1 when executed by the processing unit.

13. The apparatus according to claim 1 , wherein the processing unit is configured to determine the pressure drop using a lumped element fluid dynamics model including the at least one resistance value and the boundary conditions.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2019
From: HAASE, CHRISTIAN; GRASS, MICHAEL; VAN RENS, BRAM ANTONIUS PHILOMENA; BULLENS, ROLAND WILHELMUS MARIA; RONGEN, PETER MARIA JOHANNES; VAN DER HORST, ARJEN; FLORENT, RAOUL; GAURIAU, ROMANE ISABELLE MARIE-BERNARD; OLIVIAN BESCOS, JAVIER; SCHMITT, HOLGER; AUVRAY, VINCENT MAURICE ANDRE
To: KONINKLIJKE PHILIPS N.V.
Reel/Frame 048777/0921 →
Priority Claims (1)
EP 16191781 · Sep 30, 2016 · regional
Continuity (1)
Related Publication 20200029830A1 · Jan 30, 2020
Cited By (10)
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