IP Library › Granted Patent US 11,320,444
Granted Patent B2
US 11,320,444 · App. 16/349,011 · Granted May 3, 2022

Processing system and method for processing a microfluidic cartridge with a processing unit

Inventors: Martin Schulz (Winterbach, DE); Jochen Rupp (Stuttgart, DE); Christian Dorrer (Winnenden, DE); Karsten Seidl (Mülheim an der Ruhr, DE)
Assignee: Robert Bosch GmbH
G01N35/00732B01L3/502715B01L3/545B01L2200/14B01L2300/021B01L2300/022B01L2300/024B01L2300/0816G01N2035/00801G01N2035/00821G01N2035/00831
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Quick Facts
Patent No.
US 11,320,444
App. No.
16/349,011
Granted
May 3, 2022
Kind
B2
Abstract

A processing system includes a processing unit configured to process a cartridge, in particular a microfluidic cartridge, and is further configured to process a biological sample received in the cartridge. The processing unit includes a computing unit configured to compare input or read in sample data with input or read in first cartridge data in order to determine a compatibility of the sample with the cartridge. The computing unit is further configured to output a first error message in response to a determination of incompatibility between the sample and the cartridge. A method includes using the processing system to determine a compatibility between a sample and a cartridge.

Claims (45)

1. A method for processing a cartridge and a biological sample received into the cartridge, with a processing unit, comprising:

before inserting the sample into the cartridge and before the cartridge is received into the processing unit:

entering or scanning sample data into the processing unit;

entering or scanning first cartridge data into the processing unit using a first scanning device of the processing unit; and

comparing the sample data against the first cartridge data, via the processing unit, to determine a compatibility of the sample with the cartridge; and

selectively, with reference to the determined compatibility:

in response to determining no compatibility of the sample with the cartridge via the processing unit, outputting a first error message via the processing unit;

in response to no output of the first error message:

inserting the sample into the cartridge;

inserting the cartridge into the processing unit for further processing,

scanning second cartridge data from the cartridge into the processing unit after inserting the cartridge into the processing unit using a second scanning device of the processing unit;

comparing the first cartridge data with the second cartridge data, via the processing unit, to determine whether the second cartridge data includes an identical identification data set with the first cartridge data; and

in response to the second cartridge data not including the identical identification data set with the first cartridge data, outputting a second error message via the processing unit.

2. The method as claimed in claim 1 , wherein in response to completion of the further processing, depositing first information about the completed processing of the cartridge in a memory.

3. The method as claimed in claim 1 , wherein in response to a determination that the cartridge is unusable during processing of the first or second cartridge data, storing second information about the non-usability in a memory of the cartridge.

4. The method as claimed in claim 1 , further composing:

selectively issuing an error message, via the processing unit, in response to either of (i) a determination of non-usability of the cartridge during processing of the first or second cartridge data, and (ii) detecting second information about already completed use of the cartridge during processing of the first or second cartridge data.

5. The method as claimed in claim 1 , further comprising:

comparing, via the processing unit, an expiry date of the cartridge included in the first or second cartridge data is compared with a current date; and

in response to a determination that the current date exceeds the expiry date, issuing an error message via the processing unit.

6. The method as claimed in claim 1 , wherein the first cartridge data is read in via an optical scanning of the first cartridge data applied to an outer side of the cartridge.

7. The method as claimed in claim 1 , further comprising:

selectively setting a kill-switch configured to irreversibly destroy a transponder comprising one or more of the first and second cartridge data in response to either of:

a determination that an expiry date of the cartridge is exceeded; and

an already completed use of the cartridge is detected by the processing unit.

8. The method as claimed in claim 1 , wherein:

one or more of the first and second cartridge data is stored in a memory of the cartridge; and

the method further comprises deleting the one or more of the first and second cartridge data in response to a determination that either of:

an expiry date of the cartridge has been exceeded; and

first information about already completed use of the cartridge is detected by the processing unit.

9. The method of claim 1 , wherein the cartridge is a microfluidic cartridge.

10. The method of claim 2 , wherein the first information is deposited as a part of the first or second cartridge data.

11. The method of claim 3 , wherein the second information is deposited as a part of the first or second cartridge data.

12. The method of claim 6 , wherein the first cartridge data is applied to the cartridge in the form of a one- or two-dimensional code.

13. A method for processing a cartridge and a biological sample received into the cartridge, with a processing unit, comprising:

before inserting the sample into the cartridge and before the cartridge is received into the processing unit:

entering or scanning sample data into the processing unit;

entering or scanning first cartridge data into the processing unit; and

comparing the sample data against the first cartridge data, via the processing unit, to determine a compatibility of the sample with the cartridge; and

selectively, with reference to the determined compatibility:

in response to determining no compatibility of the sample with the cartridge via the processing unit, outputting a first error message via the processing unit; and

in response to no output of the first error message:

inserting the sample into the cartridge; and

inserting the cartridge into the processing unit for further processing,

wherein in response to completion of the further processing, depositing first information about the completed processing of the cartridge in a memory of the cartridge.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2019
From: SCHULZ, MARTIN; RUPP, JOCHEN; DORRER, CHRISTIAN; SEIDL, KARSTEN
To: ROBERT BOSCH GMBH
Reel/Frame 049421/0493 →
Priority Claims (1)
DE 10 2016 222 075.6 · Nov 10, 2016 · national
Continuity (1)
Related Publication 20190265259A1 · Aug 29, 2019