Tamper-resistant enclosures for fluid lines

1. A tamper-resistant device for holding at least a first portion of an access port of a medical fluid line, the first portion of the access port comprising a threaded region that defines a first major diameter, and a distal end of the access port defining a second major diameter smaller than the first major diameter, the device comprising:

a first housing member comprising a first recess and a first stopping shelf;

a second housing member comprising a second recess and a second stopping shelf, the second housing member being configured to couple with the first housing member such that the first and second recesses cooperate to define a cavity sized to receive the first portion of the access port of the fluid line, such that the first and second stopping shelves cooperate to retain at least the first portion of the access port within the cavity;

a locking mechanism configured to maintain the first and second housing members in a coupled state when the locking mechanism is engaged; and

a tamper-evident indicator that, when activated, permits the first and second housing members to transition from the coupled state to a decoupled state to permit access to the first portion of the access port of the fluid line, wherein the tamper-evident indicator comprises a hinge coupled to each of the first and second housing members, wherein the hinge is configured to be removed from each of the first and second housing members by axial rotation of the hinge relative to the first and second housing members.

2. The tamper-resistant device of claim 1 , wherein the hinge is positioned opposite each of the first and second shelves.

3. The tamper-resistant device of claim 1 , wherein the first housing member, the second housing member, and the hinge are integrally formed of a unitary piece of material.

4. The tamper-resistant device of claim 1 , wherein removal of the hinge from the first and second housing members permits the first and second housing members to transition from the coupled state to the decoupled state.

5. The tamper-resistant device of claim 1 , wherein the hinge is coupled to the first housing member via a first breakaway mechanism and is coupled to the second housing member via a second breakaway mechanism.

6. The tamper-resistant device of claim 1 , wherein the hinge is coupled to the first housing member via a first frangible connection and is coupled to the second housing member via a second frangible connection.

7. The tamper-resistant device of claim 1 , wherein the hinge comprises a living hinge.

8. The tamper-resistant device of claim 1 , wherein the locking mechanism comprises a second tamper-evident indicator.

9. The tamper-resistant device of claim 1 , wherein the locking mechanism is configured to engage automatically when the first and second housing members are transitioned to the coupled state.

10. The tamper-resistant device of claim 1 , wherein the locking mechanism is configured to be inaccessible once engaged to prevent disengagement of the locking mechanism.

11. The tamper-resistant device of claim 1 , further comprising a sticker configured to contact both of the first and second housing members when the first and second housing members are in the coupled state, wherein activation of the sticker comprises removing at least a portion of the sticker from the first and second housing members.

12. The tamper-resistant device of claim 1 , wherein the first housing member comprises a first closed end opposite the first stopping shelf and the second housing member comprises a second closed end opposite the second stopping shelf.

13. The tamper-resistant device of claim 1 , wherein each of the first and second housing members defines a separate opening through which the locking mechanism extends.

14. The tamper-resistant device of claim 1 , wherein the threaded region comprises threads that define a separation distance between adjacent threading portions, and wherein at least one of the first and second stopping shelves defines a thickness that is larger than the separation distance.

15. A tamper-resistant device for holding an access portion of a medical fluid line, the device comprising:

a first housing member comprising a first recess;

a second housing member comprising a second recess, the second housing member being configured to couple with the first housing member such that the first and second recesses cooperate to define a cavity sized to receive the access portion of the fluid line;

a locking mechanism configured to maintain the first and second housing members in a coupled state when the locking mechanism is engaged; and

a hinge coupled to the first housing member via a first breakaway mechanism and coupled to the second housing member via a second breakaway mechanism,

wherein when the first and second housing members are in the coupled state and the locking mechanism is engaged, removal of the hinge from the first and second housing members via axial rotation of the hinge at the first and second breakaway mechanisms permits the first and second housing members to be transitioned from the coupled state to a decoupled state to permit access to the access portion of the fluid line.

16. The tamper-resistant device of claim 15 , wherein the first housing member, the second housing member, and the hinge are integrally formed of a unitary piece of material.