IP Library › Granted Patent US 10,493,060
Granted Patent B2
US 10,493,060 · App. 16/354,949 · Granted Dec 3, 2019

Spirocyclic compounds

Inventors: Peter Qinhua Huang (San Diego, CA); Mehmet Kahraman (San Diego, CA); Deborah Helen Slee (Encinitas, CA); Kevin Duane Bunker (Escondido, CA); Chad Daniel Hopkins (San Diego, CA); Joseph Robert Pinchman (San Diego, CA); Sunny Abraham (San Diego, CA); Rakesh Kumar Sit (San Diego, CA); Daniel Lee Severance (San Diego, CA)
Assignee: Recurium IP Holdings, LLC
A61K31/4162A61K31/416A61P35/00C07D471/10C07D487/10
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Quick Facts
Patent No.
US 10,493,060
App. No.
16/354,949
Granted
Dec 3, 2019
Kind
B2
Abstract

Disclosed herein are spirocyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.

Claims (17)

1. A compound selected from the group consisting of:

or a pharmaceutically salt of any of the foregoing.

2. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

3. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

4. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

5. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

6. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

7. The compound of claim 1 , wherein the compound is

8. The compound of claim 1 , wherein the compound is

9. The compound of claim 1 , wherein the compound is

10. The compound of claim 1 , wherein the compound is

11. The compound of claim 1 , wherein the compound is

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2019
From: HUANG, PETER QINHUA; KAHRAMAN, MEHMET; SLEE, DEBORAH HELEN; BUNKER, KEVIN DUANE; HOPKINS, CHAD DANIEL; PINCHMAN, JOSEPH ROBERT; ABRAHAM, SUNNY; SIT, RAKESH KUMAR; SEVERANCE, DANIEL LEE
To: KALYRA PHARMACEUTICALS, INC.
Reel/Frame 050326/0872 →
CHANGE OF NAME Recorded Sep 10, 2019
From: ZENO ROYALTIES & MILESTONES, LLC
To: RECURIUM IP HOLDINGS, LLC
Reel/Frame 050334/0330 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2019
From: KALYRA PHARMACEUTICALS, INC.
To: ZENO ROYALTIES & MILESTONES, LLC
Reel/Frame 050279/0527 →
Continuity (3)
Division 15563926
Provisional Application 62142946 · Apr 3, 2015
Related Publication 20190201380A1 · Jul 4, 2019