IP Library Granted Patent US 10,966,920
Granted Patent B2
US 10,966,920 · App. 16/374,560 · Granted Apr 6, 2021

Effervescent tablets that include crystalline sugar binder and methods of making the same

Inventors: Carrie Kraling (Minneapolis, MN); Sarah Olson (Minneapolis, MN); Shayna Jilek (Woodbury, MN)
Assignee: Amerilab Technologies, Inc.
A61K9/0007A61K9/0056A61K9/0095A61K9/1623A61K9/1664A61K9/205A61K9/2018A61K9/2068C13B50/002C13B50/02
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Quick Facts
Patent No.
US 10,966,920
App. No.
16/374,560
Granted
Apr 6, 2021
Kind
B2
Abstract

An effervescent tablet that exhibits rapid disintegration is disclosed. The effervescent tablet includes an effervescent agent that includes an acid and a base, a crystalline sugar binder selected from the group consisting of crystalline dextrose, crystalline sucrose, crystalline fructose, and combinations thereof, the crystalline sugar binder being essentially free of excipients, a sweetener that includes at least one of Stevia and Monk fruit, a flavor agent that includes a gum Arabic carrier, and optionally a lubricant derived from rice hulls (e.g., a multi-component integral lubricant).

Claims (22)

1. An effervescent tablet comprising:

at least 20% by weight of an effervescent agent comprising an acid and a base;

a sweetener comprising Stevia, Monk fruit, or a combination thereof;

from 20% by weight to 55% by weight of a first sugar binder selected from the group consisting of unagglomerated dextrose crystals, unagglomerated sucrose crystals, unagglomerated fructose crystals, and combinations thereof, the sugar binder being essentially free of excipients; and

least 1.5% by weight of a flavor agent comprising gum Arabic,

the effervescent tablet having a weight of at least 4 grams and a hardness of at least 5 kiloponds and exhibiting a disintegration time of no greater than 4 minutes and 20 seconds when tested according to the Disintegration Time Test Method.

2. The effervescent tablet of claim 1 , wherein the sugar binder comprises unagglomerated dextrose monohydrate crystals.

3. The effervescent tablet of claim 1 , wherein the sugar binder comprises unagglomerated dextrose monohydrate crystals and unagglomerated fructose crystals.

4. The effervescent tablet of claim 1 , wherein the tablet disintegrates in 25° C. water in no greater than 3.5 minutes.

5. The effervescent tablet of claim 1 comprising from 0.4% by weight to 2% by weight of the sweetener.

6. The effervescent tablet of claim 2 comprising

from 20% by weight to 55% by weight of the unagglomerated dextrose monohydrate crystals sugar binder.

7. The effervescent tablet of claim 6 comprising from 0.4% by weight to 2% by weight of the sweetener.

8. The effervescent tablet of claim 1 further comprising oil.

9. The effervescent tablet of claim 1 further comprising avocado oil.

10. The effervescent tablet of claim 1 further comprising at least 0.50% by weight oil.

11. The effervescent tablet of claim 1 having a hardness of at least 6 kiloponds.

12. The effervescent tablet of claim 1 , comprising at least 2% by weight of the flavor agent that comprises gum Arabic.

13. The effervescent tablet of claim 1 , wherein the tablet is free of flavor agents that are free of gum Arabic.

14. The effervescent tablet of claim 2 further comprising a lubricant derived from rice hulls.

15. The effervescent tablet of claim 1 further comprising a multi-component integral lubricant comprising rice hull particles, gum Arabic, sunflower oil and at least one extract of rice.

16. The effervescent tablet of claim 1 further comprising a lubricant derived from rice hulls.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2019
From: KRALING, CARRIE; OLSON, SARAH; JILEK, SHAYNA
To: AMERILAB TECHNOLOGIES, INC.
Reel/Frame 048786/0723 →
Continuity (2)
Provisional Application 62774112 · Nov 30, 2018
Related Publication 20200170935A1 · Jun 4, 2020