IP Library Granted Patent US 10,864,148
Granted Patent B2
US 10,864,148 · App. 16/378,427 · Granted Dec 15, 2020

Compositions and methods for stabilization of retinoids

Inventors: Daniel Isaacs (Elstree, GB); Elliot Isaacs (Elstree, GB); Kavitha Murugesan (Elstree, GB)
Assignee: Pangaea Laboratories Ltd.
A61K8/31A61K8/06A61K8/11A61K8/671A61K8/738A61K8/84A61K8/9789A61Q19/08
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Quick Facts
Patent No.
US 10,864,148
App. No.
16/378,427
Granted
Dec 15, 2020
Kind
B2
Abstract

The present invention relates to a composition and method for stabilisation of compounds including retinoids using the synergistic effects of beta-carotene and sodium polyaspartate.

Claims (25)

1. A cosmetic composition comprising:

retinaldehyde; beta-carotene; and

sodium polyaspartate.

2. The cosmetic composition according to claim 1 , wherein the beta-carotene is synthetic beta-carotene, isolated beta-carotene, or a plant extract containing beta-carotene.

3. The cosmetic composition according to claim 2 , wherein the ratio of synthetic beta carotene or isolated beta carotene to sodium polyaspartate is 1:0.1 to 1:10.

4. The cosmetic composition according to claim 2 , wherein the plant extract is from carrot.

5. The cosmetic composition according to claim 4 , wherein the carrot extract is at least one of carrot root extract and carrot seed oil extract.

6. The cosmetic composition according to claim 5 , wherein the ratio of carrot extract to sodium polyaspartate is 100:1 to 10:1.

7. The cosmetic composition according to claim 6 , wherein the ratio of carrot extract to sodium polyaspartate is 40:1 to 15:1.

8. The cosmetic composition according to claim 1 , wherein the concentration of retinaldehyde is up to 0.1% weight, wherein the weight percentage is based on total composition weight.

9. The cosmetic composition according to claim 1 , wherein the retinaldehyde is cyclodextrin encapsulated.

10. A stabilising composition comprising:

beta-carotene;

sodium polyaspartate; and

retinaldehyde, wherein the beta-carotene and sodium polyaspartate stabilise the retinaldehyde.

11. The stabilising composition according to claim 10 , wherein the beta-carotene is synthetic beta-carotene, isolated beta-carotene, or a plant extract containing beta-carotene.

12. A method of stabilising retinaldehyde, the method comprising:

providing a composition comprising beta-carotene, sodium polyaspartate, and retinaldehyde.

13. The method according to claim 12 , wherein the beta-carotene is synthetic beta-carotene, isolated beta-carotene, or a plant extract containing beta-carotene.

14. The method according to claim 13 , wherein the ratio of synthetic beta carotene or isolated beta carotene to sodium polyaspartate is 1:0.1 to 1:10.

15. The method according to claim 13 , wherein the plant extract is from carrot.

16. The method according to claim 15 , wherein the carrot extract at least one of carrot root extract and carrot seed oil extract.

17. The method according to claim 16 , wherein the ratio of carrot extract to sodium polyaspartate is 100:1 to 10:1.

18. The method according to claim 16 , wherein the ratio of carrot extract to sodium polyaspartate is 40:1 to 15:1.

19. The method according to claim 12 , wherein the concentration of retinaldehyde is up to 0.1% weight, wherein the weight percentage is based on total composition weight.

Assignments (2)
CHANGE OF NAME Recorded Feb 5, 2024
From: PANGAEA LABORATORIES LIMITED
To: MEDIK8 LIMITED
Reel/Frame 066340/0049 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 10, 2019
From: ISAACS, ELLIOT; ISAACS, DANIEL; MURUGESAN, KAVITHA
To: PANGAEA LABORATORIES LTD.
Reel/Frame 048848/0915 →
Priority Claims (1)
GB 1805798.4 · Apr 6, 2018 · national
Continuity (1)
Related Publication 20190307662A1 · Oct 10, 2019