IP Library Granted Patent US 10,870,022
Granted Patent B2
US 10,870,022 · App. 16/379,188 · Granted Dec 22, 2020

Topical cosmetic compositions

Inventors: Michelle Hines (Hickory Creek, TX); Geetha Kalahasti (Plano, TX); Tiffany Florence (Dallas, TX); David Gan (Southlake, TX)
Assignee: Mary Kay Inc.
A61Q19/00A61K8/31A61K8/342A61K8/345A61K8/37A61K8/375A61K8/41A61K8/55A61K8/673A61K8/8152A61K8/8194A61K8/891A61K8/895A61K8/922A61K8/9789A61K9/0014A61K36/33A61Q19/08A61K2800/30A61K2800/78A61K2800/782A61K2800/87
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Quick Facts
Patent No.
US 10,870,022
App. No.
16/379,188
Granted
Dec 22, 2020
Kind
B2
Abstract

Disclosed are compositions and methods for their use for reducing tumor necrosis factor alpha (TNF-α) and/or vascular endothelial growth factor (VEGF) production in skin cells by topically applying to skin in need thereof, a composition comprising an effective amount of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or both, or extracts thereof, to reduce TNF-α or VEGF production in skin cells.

Claims (45)

1. A method of treating inflamed skin by reducing tumor necrosis factor alpha (TNF-α) or vascular endothelial growth factor (VEGF) production in skin cells, the method comprising topically applying to inflamed skin a composition comprising an aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof, to reduce TNF-α or VEGF production in skin cells to treat the inflamed skin, wherein the composition is applied to the periorbital area of a person's face.

2. The method of claim 1 , wherein the composition comprises the aqueous extract of Opuntia ficus - indica tuna.

3. The method of claim 1 , wherein the inflamed skin is erythemic skin.

4. The method of claim 1 , wherein the inflamed skin is rosacea or psoriasis.

5. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 5 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales, or a combination thereof.

6. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 2 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof.

7. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 1 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof.

8. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 0.5 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof.

9. The method of claim 1 , wherein the composition further comprises at least 50 wt. % water.

10. The method of claim 1 , wherein the composition is applied to a fine line or wrinkle.

11. The method of claim 1 , wherein the composition does not include a hydrocarbon, a silicone fluid, an organic sunscreen, chia seed oil, an extract of common mallow, a hydrogenated polymer, and a glyceryl glucoside.

12. The method of claim 1 , wherein the composition comprises the aqueous extract of Opuntia ficus - indica nopal.

13. The method of claim 1 , wherein the composition is an emulsion.

14. The method of claim 13 , wherein the emulsion is an oil-in-water emulsion.

15. The method of claim 1 , wherein the composition is a gel.

16. The method of claim 1 , wherein the composition is a solution.

17. A method of treating inflamed skin by reducing tumor necrosis factor alpha (TNF-α) or vascular endothelial growth factor (VEGF) production in skin cells, the method comprising topically applying to inflamed skin a composition comprising an aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof, to reduce TNF-α or VEGF production in skin cells to treat the inflamed skin, wherein the composition comprises further comprises:

60 to 70 wt. % water

butylene glycol;

cyclopentasiloxane;

hydrogenated polydecene;

dimethicone/vinyl dimethicone cross polymer;

capryl glycol;

1,2-hexanediol;

hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer;

polysorbate 20;

squalane; and

panthenol.

18. A method of treating inflamed skin by reducing tumor necrosis factor alpha (TNF-α) or vascular endothelial growth factor (VEGF) production in skin cells, the method comprising topically applying to inflamed skin a composition comprising an aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof, to reduce TNF-α or VEGF production in skin cells to treat the inflamed skin, wherein the composition further comprises:

water;

glycerin;

acrylates/C 10-30 alkyl acrylate crosspolymer;

disodium ethylenediaminetetraacetic acid;

triethanolamine;

polydimethylsiloxane;

polymethyl methylacrylate;

glyceryl stearate;

pentylene glycol;

ethylhexyl isononanoate;

cetyl alcohol;

butyrosperum parkii butter;

Zea mays germ oil;

cetyl phosphate;

cetearyl alcohol; and

ceteareth-33.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2024
From: MARY KAY INC.
To: ALLUSTRA TECHNOLOGIES LLC
Reel/Frame 069009/0384 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 22, 2022
From: KALAHASTI, GEETHA
To: MARY KAY INC.
Reel/Frame 061984/0686 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2019
From: HINES, MICHELLE; KALAHASTI, GEETHA; FLORENCE, TIFFANY; GAN, DAVID
To: MARY KAY INC.
Reel/Frame 048839/0523 →
Continuity (3)
Continuation 15378597 · Dec 14, 2016
Provisional Application 62269509 · Dec 18, 2015
Related Publication 20190231675A1 · Aug 1, 2019