Carotid sinus nerve stimulation

1. A method for stimulating nerve fibers to treat a condition in a patient, the method comprising:

identifying carotid sinus nerve afferent fibers in a first side of a patient's neck;

identifying cardiac-specific vagal nerve afferent fibers in the first side of the patient's neck;

placing a first multipolar electrode device around the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers;

stimulating the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers, using the first multipolar electrode device;

sensing a heart rate of the patient; and

timing the stimulation of the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers to the sensed heart rate, wherein timing the stimulation comprises:

delivering 25 percent of a pulse train of the stimulation at the onset of a sensed signal corresponding to a systolic phase of the patient's heartbeat; and

delivering a remaining 75 percent of the pulse train during a diastolic phase of the patient's heartbeat.

2. The method of claim 1 , wherein stimulating the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers comprises sending a stimulation signal from a pulse generator implanted in the patient through a first lead to the first multipolar electrode device.

3. The method of claim 1 , wherein identifying the carotid sinus nerve afferent fibers comprises identifying a nerve plexus near the carotid sinus.

4. The method of claim 1 , further comprising:

identifying carotid sinus nerve afferent fibers in a second side of the patient's neck;

identifying cardiac-specific vagal nerve afferent fibers in the second side of the patient's neck;

placing a second multipolar electrode device around the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers in the second side; and

stimulating the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers in the second side, using the second multipolar electrode device.

5. The method of claim 4 , wherein stimulating the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers comprises:

sending a first stimulation signal from a pulse generator implanted in the patient through a first lead to the first multipolar electrode device; and

sending a second stimulation signal from a pulse generator implanted in the patient through a second lead to the second multipolar electrode device.

6. The method of claim 1 , wherein the multipolar electrode device is a hexapolar electrode.

7. The method of claim 1 , wherein stimulating the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers comprises providing a stimulation signal with parameters in the ranges of 1-25 mA amplitude, 0.06-5 ms pulse widths and 1-5000 Hz frequency.

8. The method of claim 7 , wherein stimulation is at a frequency of between 80 Hz and 120 Hz.

9. The method of claim 8 , wherein timing the stimulation comprises adjusting a frequency of the stimulation such that a number of delivered electrical impulses is constant for each cardiac cycle of the patient's heart.

10. The method of claim 8 , wherein sensing the heart rate comprises using data selected from the group consisting of an electrocardiogram, a blood pressure waveform, a phonocardiograph and an arterial distension waveform.

11. The method of claim 8 , wherein timing the stimulation comprises delivering all of a pulse train of the stimulation during a diastolic phase of the patient's heartbeat.

12. The method of claim 1 , wherein stimulating the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers comprises selectively stimulating only afferent nerve fibers and not stimulating efferent nerve fibers.

13. An implantable system for stimulating nerve fibers to treat a condition in a patient, the system comprising:

a pulse generator;

a first multipolar electrode device configured to wrap around carotid sinus nerve afferent fibers and cardiac-specific vagal nerve afferent fibers in a first side of a patient's neck;

a first lead attached at one end to the pulse generator and at an opposite end to the first multipolar electrode device; and

a computing device wirelessly connected to the pulse generator and configured to receive a sensed heart rate from an electrocardiogram sensor and transmit at least one stimulation parameter to the pulse generator,

wherein the computing device is configured to time a stimulation of the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers to the sensed heart rate, wherein timing the stimulation comprises:

delivering 25 percent of a pulse train of the stimulation at the onset of a sensed signal corresponding to a systolic phase of the patient's heartbeat; and

delivering a remaining 75 percent of the pulse train during a diastolic phase of the patient's heartbeat.

14. The system of claim 13 , wherein the first multipolar electrode device is a hexapolar electrode.

15. The system of claim 14 , wherein the first multipolar electrode device is flexible and has two flaps connected along one edge and open along an opposite edge, wherein the open opposite edge is configured to admit the carotid sinus nerve afferent fibers and cardiac-specific vagal nerve afferent fibers.

16. The system of claim 13 , further comprising:

a second multipolar electrode device configured to wrap around carotid sinus nerve afferent fibers and cardiac-specific vagal nerve afferent fibers in a second side of the patient's neck; and

a second lead attached at one end to the pulse generator and at an opposite end to the second multipolar electrode device.

17. The system of claim 16 , wherein the system comprises the electrocardiogram sensor, the system further comprising:

a third lead attached at one end to the pulse generator and at an opposite end to the electrocardiogram sensor.

18. The system of claim 17 , wherein the electrocardiogram sensor comprises:

a paddle-shaped substrate; and

multiple electrodes positioned along the paddle-shaped substrate.

19. The system of claim 13 , wherein the first multipolar electrode device is configured to selectively stimulate the carotid sinus nerve afferent fibers and the cardiac-specific vagal nerve afferent fibers and to not stimulate efferent nerve fibers.