IP Library Patent Application 16419761
Patent Application
App. No. 16/419,761

METHODS OF TREATING EPILEPSY OR STATUS EPILEPTICUS

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Patent No.
US None
App. No.
16/419,761
Abstract

Described herein are methods of treating epilepsy or status epilepticus, e.g., convulsive status epilepticus, e.g., early status epilepticus, established status epilepticus, refractory status epilepticus, super-refractory status epilepticus, e.g., super-refractory generalized status epilepticus; non-convulsive status epilepticus, e.g., generalized status epilepticus, complex partial status epilepticus; generalized periodic epileptiform discharges; periodic lateralized epileptiform discharges; a seizure, e.g., acute repetitive seizures, cluster seizures, the method comprising administering to the subject a neuroactive steroid.

Claims (4)

1 - 164 . (canceled)

165 . A method of preparing a formulation comprising allopregnanolone, said method comprising the step of high shear mixing an aqueous 5 mg/mL solution of allopregnanolone with 25% sulfo butyl ether beta-cyclodextrin solution.

166 . The method of claim 165 , wherein the step of high shear mixing is performed for a period of time, characterized by a clear aqueous solution comprising 5 mg/mL allopregnanolone and 25% sulfo butyl ether beta-cyclodextrin.

167 . The method of claim 166 , where the period of time is at least about 30 minutes.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 6, 2021
From: KANES, STEPHEN JAY; REDDY, KIRAN
To: SAGE THERAPEUTICS, INC.
Reel/Frame 057101/0722 →