IP Library › Patent Application 16423559
Patent Application
App. No. 16/423,559

CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS

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Quick Facts
Patent No.
US None
App. No.
16/423,559
Abstract

The invention described herein pertains to the diagnosis, imaging, and/or treatment of pathogenic cell populations. In particular, the invention described herein pertains to the diagnosis, imaging, and/or treatment of diseases caused by PSMA expressing cells, such as prostate cancer cells, using compounds capable of targeting PSMA expressing cells.

Claims (4)

1 . A conjugate of the formula

B-L-(D) n

or a pharmaceutically acceptable salt thereof, wherein B comprises a urea or thiourea of lysine and an amino acid, or one or more carboxylic acid derivatives thereof, including, but not limited to ureas or thioureas of lysine and aspartic acid, or glutamic acid, or homoglutamic acid, where the urea or thiourea is capable of binding to PSMA, L is a polyvalent linker, D is a radical of a drug, and n is an integer selected from 1, 2, 3, and 4.

2 - 29 . (canceled)

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 22, 2023
From: VLAHOV, IONTCHO RADOSLAVOV; REDDY, JOSEPH ANAND; BLOOMFIELD, ALICIA; DORTON, RYAN; NELSON, MELISSA; VETZEL, MARILYNN; LEAMON, CHRISTOPHER PAUL
To: ENDOCYTE, INC.
Reel/Frame 065945/0301 →