IP Library Granted Patent US 10,647,668
Granted Patent B2
US 10,647,668 · App. 16/431,255 · Granted May 12, 2020

Isothiocyanate functional surfactant and associated method of use

Inventor: Michael E. Silver (Lake City, MI)
Assignee: The William M. Yarbrough Foundation
C07C331/20A61K9/0014A61K31/145A61K31/198A61K31/26A61K45/06A61K47/34
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Quick Facts
Patent No.
US 10,647,668
App. No.
16/431,255
Granted
May 12, 2020
Kind
B2
Abstract

A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.

Claims (11)

1. An isothiocyanate functional surfactant, comprising:

a lysine derivative having an α-nitrogen and an ε-nitrogen, and wherein an alkyl substituent comprising at least 8 carbon atoms is bound to the α-nitrogen, and further wherein the ε-nitrogen forms part of an isothiocyanate functional group.

2. The isothiocyanate functional surfactant according to claim 1 , in combination with an additional surfactant selected from at least one of the group comprising a non-ionic surfactant, an anionic surfactant, a cationic surfactant, a zwitterionic surfactant, and combinations thereof.

3. The isothiocyanate functional surfactant according to claim 2 , wherein the additional surfactant comprises a non-ionic surfactant.

4. The isothiocyanate functional surfactant according to claim 3 , wherein the non-ionic surfactant is selected from at least one of the group comprising alcohols, alkanolamides, amine oxides, esters, glycerides, ethoxylated glycerides, polyglyceryl esters, sorbitan esters, carbohydrate esters, ethoxylated carboxylic acids, phosphoric acid triesters, ethers, ethoxylated alcohols, alkyl glucosides, ethoxylated polypropylene oxide ethers, alkylated polyethylene oxides, alkylated polypropylene oxides, alkylated PEG/PPO copolymers, and combinations thereof.

5. The isothiocyanate functional surfactant according to claim 2 , wherein the additional surfactant comprises an anionic surfactant.

6. The isothiocyanate functional surfactant according to claim 5 , wherein the anionic surfactant is selected from at least one of the group comprising taurates, isethionates, alkyl sulfates, alkyl ether sulfates, succinamates, alkyl sulfonates, alkylaryl sulfonates, olefin sulfonates, alkoxy alkane sulfonates, salts of fatty acids derived from natural plant and/or animal sources and/or synthetically prepared, alkylated ammonium salts of alkylated and/or acylated amino acids and/or peptides, alkylated sulfoacetates, alkylated sulfosuccinates, acylglyceride sulfonates, alkoxyether sulfonates, phosphoric acid esters, phospholipids, and combinations thereof.

7. The isothiocyanate functional surfactant according to claim 2 , wherein the additional surfactant comprises a cationic surfactant.

8. The isothiocyanate functional surfactant according to claim 7 , wherein the cationic surfactant is selected from at least one of the group comprising alkylated quaternary ammonium salts R 4 NX, alkylimidazolines, alkoxylated amines, and combinations thereof.

9. The isothiocyanate functional surfactant according to claim 2 , wherein the additional surfactant comprises a zwitterionic surfactant.

10. The isothiocyanate functional surfactant according to claim 9 , wherein the zwitterionic surfactant is selected from at least one of the group comprising betaines, sultaines, hydroxysultaines, amido betaines, amidosulfo betaines, and combinations thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 24, 2019
From: SILVER, MICHAEL E.
To: THE WILLIAM M. YARBROUGH FOUNDATION
Reel/Frame 050473/0060 →
Continuity (7)
Continuation 15943810 · Apr 3, 2018
Continuation 14880418 · Oct 12, 2015
Continuation 14594788 · Jan 12, 2015
Continuation 13342516 · Jan 3, 2012
Provisional Application 61502067 · Jun 28, 2011
Provisional Application 61429325 · Jan 3, 2011
Related Publication 20190284133A1 · Sep 19, 2019
Cited By (2)
US 12,239,626 US 12,310,939