IP Library Granted Patent US 11,590,092
Granted Patent B2
US 11,590,092 · App. 16/432,864 · Granted Feb 28, 2023

Skin probiotic

Inventor: Chun-Ming Huang (San Diego, CA)
Assignee: The Regents of the University of California
A61K31/19A61K9/0014A61K9/06A61K31/047A61K31/194A61K31/22A61K31/225A61K35/741A61K45/06C12Q1/04A61K2035/115G01N2500/10
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Quick Facts
Patent No.
US 11,590,092
App. No.
16/432,864
Granted
Feb 28, 2023
Kind
B2
Abstract

The disclosure provides skin probiotics, fermented media extract and fermentation byproducts thereof for the treatment of skin disease and disorders as well as for the prevention/treatment of acne and MRSA.

Claims (11)

1. A topical probiotic composition for producing or maintaining skin microbiome balance, the composition comprising

and one or more excipients for formulation as a lotion, shake lotion, soap, wipe, cream, spray, ointment, gel, foam, powder, solid, paste or tincture.

2. The topical probiotic composition of claim 1 , capable of inhibiting the growth or spread of S. aureus or a methicillin-resistant S. aureus (MRSA) on skin.

3. The topical probiotic composition of claim 1 , capable of inhibiting or preventing the infection of S. aureus , methicillin-resistant S. aureus (MRSA), a Candida species, or E. coli on skin.

4. The topical probiotic composition of claim 1 , further comprising at least one probiotic commensal skin bacteria fermentation extract.

5. The topical probiotic composition of claim 4 , wherein the probiotic commensal skin bacteria is selected from the group consisting of a Propionibacterium species, a Paenibacillus species, and a Staphylococcus species.

6. The topical probiotic composition of claim 1 , further comprising glycerol.

7. The topical probiotic composition of claim 1 , wherein the composition is formulated as a lotion, shake lotion, cream, ointment, gel, foam, powder, solid, paste or tincture.

8. A bandage or dressing comprising the topical probiotic composition of claim 1 .

9. A method of treating or preventing a skin infection, the method comprising contacting the skin with the topical probiotic composition of claim 1 .

10. The method of claim 9 , wherein the skin infection is caused by S. aureus , methicillin-resistant S. aureus (MRSA), a Candida species, or E. coli.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 21, 2023
From: HUANG, CHUN-MING
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 062446/0055 →
CONFIRMATORY LICENSE Recorded Mar 17, 2020
From: UNIVERSITY OF CALIFORNIA SAN DIEGO
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 052183/0442 →
Continuity (3)
Division 15110730
Provisional Application 61926055 · Jan 10, 2014
Related Publication 20190282523A1 · Sep 19, 2019