IP Library › Granted Patent US 10,774,100
Granted Patent B2
US 10,774,100 · App. 16/460,332 · Granted Sep 15, 2020

Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same

Inventors: Hiroaki Yuasa (Tokushima, JP); Hiroki Okazaki (Tokushima, JP)
Assignees: OTSUKA CHECMIAL CO., LTD.; SANSHO CO., LTD.
C07F9/657163A61P19/00A61P29/00A61P35/00C07F9/65742C07F9/657181A61K31/665C07B2200/13
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Quick Facts
Patent No.
US 10,774,100
App. No.
16/460,332
Granted
Sep 15, 2020
Kind
B2
Abstract

An object t of the present invention is to proroaide crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):

Claims (4)

1. A method for producing a compound represented by formula (6):

wherein two R 1 groups are the same or different and represent alkyl, arylalkyl, or aryl; and two R 2 groups are the same or different and represent alkyl, cycloalkyl, or aryl, the method comprising

step (I)) of reacting a compound represented by formula (5):

wherein R 2 is as defined above; and X represents a halogen atom with a phosphorous acid diester.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2021
From: OTSUKA CHEMICAL CO., LTD.
To: OTSUKA CHEMICAL CO., LTD.; SANSHO CO., LTD.
Reel/Frame 055311/0364 →
Priority Claims (1)
JP 2014-164423 · Aug 12, 2014 · national
Continuity (3)
Division 15872321 · Jan 16, 2018
Division 15501525
Related Publication 20190330251A1 · Oct 31, 2019