IP Library Granted Patent US 11,253,493
Granted Patent B2
US 11,253,493 · App. 16/479,748 · Granted Feb 22, 2022

Compositions and methods affecting exercise performance

Inventors: Christoph Westphal (Boston, MA); Thomas Wessel (Lenox, MA)
Assignee: Cliff-Cartwright Corporation
A61K31/165A61K9/0053A61K9/0095A61K31/11A61K31/12A61P21/00
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Quick Facts
Patent No.
US 11,253,493
App. No.
16/479,748
Granted
Feb 22, 2022
Kind
B2
Abstract

Described herein are compositions comprising activators of TRP and ASIC channels that may be useful to improve or preserve exercise performance and exercise recovery.

Claims (8)

1. A method for improving or preserving physical performance during exercise in a subject, wherein the method comprises orally administering to the subject a composition comprising capsicum , ginger, cinnamon, and an excipient, wherein improving or preserving physical performance during exercise in a subject is increasing the energy of the subject, improving the mood of the subject, reducing the exertion of the subject, or reducing the pain of the subject, relative to a reference standard.

2. The method of claim 1 , wherein the method further comprises administering to the subject an amount of composition in the range of 10 mL to 1000 mL.

3. The method of claim 1 , wherein the composition is administered to the subject prior to commencement of exercise.

4. The method of claim 1 , wherein:

(a) the amount of capsicum in the composition is in the range of 0.001% (w/w) to 1% (w/w); or

(b) the amount of ginger in the composition is in the range of 0.001% (w/w) to 1% (w/w); or

(c) the amount of cinnamon in the composition is in the range of 0.001% (w/w) to 1% (w/w).

5. The method of claim 1 , wherein the excipient is selected from the group consisting of an antioxidant, a binder, a coloring agent, a disintegrant, an emulsifier, a flavoring agent, a lubricant, a pH-adjusting agent, a preservative, a surfactant, a sweetener, and viscosity modifier.

Assignments (3)
CHANGE OF NAME Recorded Feb 20, 2020
From: FLEX PHARMA, INC.
To: SALARIUS PHARMACEUTICALS, INC.
Reel/Frame 051975/0133 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 20, 2020
From: SALARIUS PHARMACEUTICALS, INC.
To: CLIFF-CARTWRIGHT CORPORATION
Reel/Frame 051975/0181 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2020
From: WESTPHAL, CHRISTOPH; WESSEL, THOMAS
To: FLEX PHARMA, INC.
Reel/Frame 051846/0842 →
Continuity (2)
Provisional Application 62449411 · Jan 23, 2017
Related Publication 20200261382A1 · Aug 20, 2020