IP Library Granted Patent US 11,090,433
Granted Patent B2
US 11,090,433 · App. 16/485,989 · Granted Aug 17, 2021

System and method for body mass index relation to patient differing psychological stress effect on blood glucose dynamics in patients with insulin dependent diabetes

Inventors: Stephen D. Patek (Charlottesville, VA); Basak Ozaslan (Charlottesville, VA); Linda Gonder-Frederick (Charlottesville, VA)
Assignee: UNIVERSITY O VIRGINIA PATENT FOUNDATION
A61M5/1723A61M5/14276G16H20/17G16H50/30G16H50/70A61M2205/3553A61M2205/3569A61M2205/3584A61M2230/201
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Quick Facts
Patent No.
US 11,090,433
App. No.
16/485,989
Granted
Aug 17, 2021
Kind
B2
Abstract

An insulin device configured to control insulin dispensing based on insulin sensitivity. The insulin device includes a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data; a sensor configured to generate a blood glucose level measurement. The sensor is calibrated as a function of the psychological stress level data and the BMI data and the processor is configured to monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and identify a time when the BMI data counteracts a detected change in the blood glucose level measurement. The insulin device also includes an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data.

Claims (32)

1. An insulin device configured to control insulin dispensing based on insulin sensitivity, the insulin device comprising:

a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data;

a sensor configured to generate a blood glucose level measurement, wherein the sensor is calibrated as a function of the psychological stress level data and the BMI data, and wherein the processor is configured to:

monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and

identify a time when the BMI data counteracts a detected change in the blood glucose level measurement; and

an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data.

2. The insulin device of claim 1 , wherein the insulin dosing schedule information is input.

3. The insulin device of claim 1 in combination with:

an insulin pump, wherein the insulin dosing schedule information is received from the insulin pump.

4. The insulin device of claim 1 , wherein the psychological stress level data is measured on a scale.

5. The insulin device of claim 4 , wherein the scale is a five point Likert scale.

6. The insulin device of claim 1 , wherein the processor is configured to correlate a detected increase in a value of the psychological stress level data with an increase in a value of the blood glucose level measurement.

7. The insulin device of claim 1 , wherein the processor is configured to correlate a detected decrease in a value of the psychological stress level data with a decrease in a value of the blood glucose level measurement.

8. The insulin device of claim 1 , wherein the processor is configured to correlate a counteraction of a BMI data increase with an increase in a value of the BMI data.

9. The insulin device of claim 8 , wherein the processor is configured to detect a decrease in a value of a blood glucose level measurement data when the increase in the value of the BMI data crosses a threshold.

10. The insulin device of claim 1 , wherein the processor is configured to correlate the counteraction by a BMI data with a higher uptake of glucose.

11. The insulin device of claim 1 in combination with:

a display, wherein the processor is configured to categorize and display the BMI data as normal BMI, overweight BMI, or obese BMI.

12. A computer-implemented method to control insulin dispensing based on insulin sensitivity, the method comprising:

receiving insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data;

generating a blood glucose level measurement as a function of the psychological stress level data and the BMI data;

monitoring and detecting changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data;

identifying a time when the BMI data counteracts a detected change in the blood glucose level measurement;

updating the insulin dosing schedule information in accordance with the counteracting BMI data; and

controlling an insulin dispensing device to provide insulin dosing based on the updated insulin dosing schedule information.

13. A non-transitory computer readable recording medium encoded with a computer program comprising program instructions causing an insulin device to control insulin dispensing based on insulin sensitivity, the program causing the insulin device to:

receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data;

generate a blood glucose level measurement as a function of the psychological stress level data and the BMI data;

monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data;

identify a time when the BMI data counteracts a detected change in the blood glucose level measurement;

update the insulin dosing schedule information in accordance with the counteracting BMI data; and

control an insulin dispensing device to provide insulin dosing based on the updated insulin dosing schedule information.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2020
From: PATEK, STEPHEN D.
To: UNIVERSITY OF VIRGINIA
Reel/Frame 053742/0905 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2020
From: OZASLAN, BASAK
To: UNIVERSITY OF VIRGINIA
Reel/Frame 053742/0944 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2020
From: UNIVERSITY OF VIRGINIA
To: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Reel/Frame 053743/0246 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2020
From: GONDER-FREDERICK, LINDA A.
To: UNIVERSITY OF VIRGINIA
Reel/Frame 053757/0696 →
CONFIRMATORY LICENSE Recorded Sep 9, 2020
From: UNIVERSITY OF VIRGINIA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 053730/0383 →
Continuity (2)
Provisional Application 62459096 · Feb 15, 2017
Related Publication 20200230319A1 · Jul 23, 2020