BILE ACID SYNTHESIS PROMOTER, COMPOSITION FOR PROMOTING BILE ACID SYNTHESIS AND FOOD COMPOSITION FOR PROMOTING BILE ACID SYNTHESIS
[Problem] To provide a novel medicine that is capable of promoting cholesterol metabolism to thereby treat, ameliorate or prevent various symptoms associated with increase in blood cholesterol level. [Solution] The present inventors newly found that arctigenin has an effect of promoting the conversion of cholesterol into bile acid. The present invention provides a bile acid synthesis promoter, a composition for promoting bile acid synthesis and a food composition for promoting bile acid synthesis each comprising arctigenin and/or arctiin as active ingredient(s).
1 . A bile acid synthesis promoter comprising arctigenin and/or arctiin as an active ingredient(s).
2 . A composition for promoting bile acid synthesis comprising arctigenin and/or arctiin as an active ingredient(s).
3 . A composition for promoting bile acid synthesis according to claim 2 comprising said arctigenin and/or arctiin as burdock, burdock fruit, burdock sprout or Forsythia fruit or extracts thereof.
4 . A food composition for promoting bile acid synthesis comprising arctigenin and/or arctiin as an active ingredient(s).
5 . A food composition for promoting bile acid synthesis according to claim 4 comprising said arctigenin and/or arctiin as burdock, burdock fruit, burdock sprout or Forsythia fruit or extracts thereof.
6 . An expression promoter of bile acid synthetic enzymes comprising arctigenin and/or arctiin as an active ingredient(s).
7 . A bile acid excretion promoter comprising arctigenin and/or arctiin as an active ingredient(s).
8 . A cholesterol metabolism promoter in the liver comprising arctigenin and/or arctiin as active ingredient(s).