IP Library Granted Patent US 11,446,520
Granted Patent B2
US 11,446,520 · App. 16/493,955 · Granted Sep 20, 2022

Radiation therapy apparatus configured to track a tracking object moving in an irradiation object

Inventors: Takaaki Fujii (Sapporo, JP); Seishin Takao (Sapporo, JP); Naoki Miyamoto (Sapporo, JP); Taeko Matsuura (Sapporo, JP); Kikuo Umegaki (Sapporo, JP)
Assignee: National Univ. Corporation Hokkaido Univ.
A61N5/1049A61B90/39A61N5/1037A61N5/1048A61N5/1064A61N5/1071A61N2005/1061
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Quick Facts
Patent No.
US 11,446,520
App. No.
16/493,955
Granted
Sep 20, 2022
Kind
B2
Abstract

Through the present invention, three-dimensional coordinates of a tracking object moving in an irradiation object can be calculated from fluoroscopic X-ray images captured and acquired from various angles in a single fluoroscopic X-ray device mounted to a radiation therapy apparatus. The three-dimensional coordinates of the tracking object are calculated on a straight tracking object presence line connecting an X-ray generating device for fluoroscopy and the position in an X-ray plane detector of the tracking object on the fluoroscopic X-ray image acquired by the X-ray generating device for fluoroscopy and the X-ray plane detector, and using line segment information included in a movement region of the tracking object set in advance.

Claims (57)

1. A radiation therapy apparatus comprising:

a couch that supports an irradiation target;

a gantry that is movable around the irradiation target to irradiate the irradiation target on the couch with therapeutic radiation from various angles;

a fluoroscopic X-ray generation device and an X-ray flat-panel detector that are installed on the gantry and configured to acquire a fluoroscopic X-ray image; and

a control system comprising:

a CBCT imaging device;

a moving-object tracking device; and

a central control unit configured to control:

the CBCT imaging device to control the fluoroscopic X-ray generation device and the X-ray flat-panel detector to acquire a cone-beam CT image; and

the moving-object tracking device to two-dimensionally track a tracking target object projected within the irradiation target in the fluoroscopic X-ray image,

wherein the CBCT imaging device calculates three-dimensional coordinates of the tracking target object as a midpoint between two intersecting points between a movement area of the tracking target object set in advance and the tracking target object passing a straight line formed by connecting to each other three-dimensional coordinates in a therapy room coordinate system for an image of the tracking target object projected on each fluoroscopic X-ray image and three-dimensional coordinates of the fluoroscopic X-ray generation device.

2. The radiation therapy apparatus according to claim 1 , wherein

the CBCT imaging device determines a respiratory phase of the irradiation target based on the three-dimensional coordinates of the tracking target object obtained for fluoroscopic X-ray images, and reconstructs a three-dimensional image of the irradiation target from a selected one or more of the fluoroscopic X-ray images in the respiratory phase.

3. A radiation therapy apparatus comprising:

a couch that supports an irradiation target;

a gantry that is movable around the irradiation target to irradiate the irradiation target on the couch with therapeutic radiation from various angles;

a fluoroscopic X-ray generation device and an X-ray flat-panel detector that are installed on the gantry and used for acquiring a fluoroscopic X-ray image; and

a control system comprising:

a CBCT imaging device;

a moving-object tracking device; and

a central control unit configured to control:

the CBCT imaging device to perform cone-beam CT imaging by using the fluoroscopic X-ray generation device and the X-ray flat-panel detector to acquire a cone-beam CT image; and

the moving-object tracking device to two-dimensionally track a tracking target object projected within the irradiation target in the fluoroscopic X-ray image, wherein

the moving-object tracking device transfers a position of each tracking target object on a four-dimensional CT image including a position of the tracking target object in each respiratory phase acquired in advance into a therapy room coordinate system, the CBCT imaging device calculates each intersecting point or a common perpendicular line between or of an inter-phase movement straight line and a tracking target object passing straight line, the CBCT imaging device obtains the inter-phase movement straight line by connecting positions of the tracking target object on the four-dimensional CT image in respiratory phases, the CBCT imaging device obtains an intersecting point as three-dimensional coordinates of the tracking target object when the intersecting point exists, and a point on the common perpendicular line on the inter-phase movement straight line, where the CBCT imaging device obtains the common perpendicular line, which has a shortest length, as the three-dimensional coordinates of the tracking target object when the intersecting point does not exist.

4. The radiation therapy apparatus according to claim 3 , wherein

the CBCT imaging device determines a respiratory phase of the irradiation target based on the three-dimensional coordinates of the tracking target object obtained for fluoroscopic X-ray images, and reconstructs a three-dimensional image of the irradiation target from a selected one or more of the fluoroscopic X-ray images in the respiratory phase.

5. A radiation therapy apparatus comprising:

a couch that supports an irradiation target;

a gantry that is movable around the irradiation target to irradiate the irradiation target on the couch with therapeutic radiation from various angles;

a fluoroscopic X-ray generation device and an X-ray flat-panel detector that are installed on the gantry and used for acquiring a fluoroscopic X-ray image; and

a control system comprising:

a CBCT imaging device;

a moving-object tracking device; and

a central control unit configured to control:

the CBCT imaging device to perform cone-beam CT imaging by using the fluoroscopic X-ray generation device and the X-ray flat-panel detector to acquire a cone-beam CT image; and

the moving-object tracking device to two-dimensionally track a tracking target object projected within the irradiation target in the fluoroscopic X-ray image, wherein

the moving-object tracking device obtains three-dimensional coordinates of the tracking target object as coordinates that are included in a movement area set in advance, the three-dimensional coordinates being on a tracking target object passing straight line formed by connecting to each other three-dimensional coordinates in a therapy room coordinate system for an image of the tracking target object projected on each fluoroscopic X-ray image and three-dimensional coordinates of the fluoroscopic X-ray generation device, and

the CBCT imaging device determines a respiratory phase of the irradiation target based on the three- dimensional coordinates of the tracking target object obtained for fluoroscopic X-ray images, and reconstructs a three-dimensional image of the irradiation target from a selected one or more of the fluoroscopic X-ray images in the respiratory phase.

6. A radiation therapy apparatus comprising:

a couch that supports an irradiation target;

a gantry that is movable around the irradiation target to irradiate the irradiation target on the couch with therapeutic radiation from various angles;

a fluoroscopic X-ray generation device and an X-ray flat-panel detector that are installed on the gantry and used for acquiring a fluoroscopic X-ray image;

a pair of moving-object tracking X-ray generation devices;

a pair of moving-object tracking X-ray flat-panel detectors; and

a control system comprising:

a CBCT imaging device;

a moving-object tracking device; and

a central control unit configured to control:

the CBCT imaging device to perform cone-beam CT imaging by using the fluoroscopic X-ray generation device and the X-ray flat-panel detector to acquire a cone-beam CT image;

the moving-object tracking device to two-dimensionally track a tracking target object projected within the irradiation target in the fluoroscopic X-ray image and to three-dimensionally track the tracking target object on a fluoroscopic X-ray image acquired with the pair of moving-object tracking X-ray generation devices and the pair of moving-object tracking X-ray flat-panel detectors,

wherein the moving-object tracking device obtains three-dimensional coordinates of the tracking target object as a point on a tracking target object passing straight line formed by connecting to each other three-dimensional coordinates in a therapy room coordinate system for an image of the tracking target object projected on a fluoroscopic X-ray image acquired during the cone-beam CT imaging and three-dimensional coordinates of the fluoroscopic X-ray generation device, the point being any one of:

(i) a point on a three-dimensional movement trajectory of the tracking target object in the therapy room coordinate system acquired from the moving-object tracking device,

(ii) a point on a three-dimensional movement trajectory of the tracking target object in the therapy room coordinate system, where a calculated common perpendicular line, at which the three- dimensional movement trajectory and the tracking target object passing straight line perpendicularly intersect, has a shortest length,

(iii) a point on a tracking target object passing straight line, where a calculated common perpendicular line, at which a three-dimensional movement trajectory of the tracking target object in the therapy room coordinate system and the tracking target object passing straight line perpendicularly intersect, has a shortest length, and

(iv) a midpoint on a length of a common perpendicular line.

7. The radiation therapy apparatus according to claim 6 , wherein

the CBCT imaging device determines a respiratory phase of the irradiation target based on the three-dimensional coordinates of the tracking target object obtained for fluoroscopic X-ray images, and reconstructs a three-dimensional image of the irradiation target from a selected one or more of the fluoroscopic X-ray images in the respiratory phase.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 28, 2020
From: FUJII, TAKAAKI; TAKAO, SEISHIN; MIYAMOTO, NAOKI; MATSUURA, TAEKO; UMEGAKI, KIKUO
To: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Reel/Frame 053897/0142 →
Priority Claims (1)
JP JP2017-047982 · Mar 14, 2017 · national
Continuity (1)
Related Publication 20200009404A1 · Jan 9, 2020
Cited By (3)
US 12,420,117 US 12,722,025 US 12,734,373