IP Library › Granted Patent US 11,338,289
Granted Patent B2
US 11,338,289 · App. 16/500,683 · Granted May 24, 2022

Microfluidic device

Inventors: Clémence Vergne (Paris, FR); Benjamin Rouffet (Lagny-sur-Marne, FR); Lionel Matthys (Villejuif, FR); Robert Breton (Paris, FR); Nicolas Petit (Sceaux, FR)
Assignee: FLUIGENT
B01L3/502738B01L3/50273G05D16/02B01L2300/14B01L2400/0487
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Quick Facts
Patent No.
US 11,338,289
App. No.
16/500,683
Granted
May 24, 2022
Kind
B2
Abstract

Microfluidic device comprising a tank ( 6 ) supplying a microchannel ( 2 ) with a first fluid (S), and a circuit ( 8 ) in which a flow of a second fluid can be established without contact with the microchannel ( 2 ). The circuit ( 8 ) passes through the tank ( 6 ) or is connected to the tank ( 6 ) by a pipe ( 30 ). The circuit ( 8 ) comprises a first on/off valve ( 12 ) mounted in parallel with a first proportional valve ( 11 ), these first valves ( 11, 12 ) being controllable so as to modify the pressure applied in the tank ( 6 ) to the first fluid (S) by the second fluid.

Claims (22)

1. A microfluidic device comprising

a tank supplying a microchannel with a first fluid and a circuit in which a flow of a second fluid can be established without contact with the microchannel,

wherein the circuit passes through the tank (this limitation is interpreted as optional) or is connected to the tank by a pipe, and

wherein the circuit comprises an on/off valve mounted in parallel with a proportional valve a maximum opening cross-section of the proportional valve being smaller than maximum opening cross-section of the on/off valve, wherein both the proportional and the on/off valves are configured to be controlled to modify a pressure applied in the tank to the first fluid by the second fluid.

2. A microfluidic device according to claim 1 , comprising a control system for controlling the on/off valve and the proportional valve so as to modify the pressure applied in the tank by the second fluid to the first fluid so that this pressure reaches a set pressure, the control system being configured for, following a change in the set pressure:

in a first phase, open the on/off valve to quickly fill or empty the tank with the second fluid and quickly reach a pressure in the tank close to the set pressure,

then close the on/off valve and control the proportional valve so that the pressure in the tank reaches and stays at the set pressure.

3. A microfluidic device according to claim 1 , wherein the maximum opening cross-section of the proportional valve is less than 20% of the maximum opening cross-section of the on/off valve.

4. A microfluidic device according to claim 1 , comprising a system for damping pressure oscillations induced by opening or closing the on/off valve.

5. A device according to claim 4 , wherein the damping system comprises an open-pore porous material placed in the circuit in series with the on/off valve and in parallel with the proportional valve.

6. A device according to claim 4 , wherein the damping system comprises a damper placed in a closed lateral branch of the circuit.

7. A microfluidic device according to claim 1 , wherein the circuit comprises a first branch and a second branch located on either side of the tank, these two branches leading directly into the tank.

8. A microfluidic device according to claim 1 , wherein the circuit comprises a first branch and a second branch located on either side of a junction between the circuit and the pipe leading to the tank.

9. A microfluidic device according to claim 7 , wherein the first branch comprises the on/off valve and the proportional valve.

10. A microfluidic device according to claim 9 , wherein the second branch comprises a narrowing formed by another proportional valve.

11. A microfluidic device according to claim 10 , wherein the second branch comprises another on/off valve mounted in parallel with the narrowing.

12. A microfluidic device according to claim 1 , wherein the first fluid is a liquid and the second fluid is a gas.

13. A microfluidic device according to claim 8 , wherein the first branch comprises the on/off valve and the proportional valve.

14. A microfluidic device according to claim 1 , wherein the maximum opening cross-section of the proportional valve is less than 5% of the maximum opening cross-section of the on/off valve.

15. A microfluidic device according to claim 8 , wherein the first branch comprises the on/off valve and the proportional valve.

16. A microfluidic device according to claim 15 , wherein the second branch comprises a narrowing formed by another proportional valve.

17. A microfluidic device according to claim 16 , wherein the second branch comprises another on/off valve mounted in parallel with the narrowing.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 19, 2019
From: VERGNE, CLÉMENCE; ROUFFET, BENJAMIN; MATTHYS, LIONEL; BRETON, ROBERT; PETIT, NICOLAS
To: FLUIGENT
Reel/Frame 051327/0934 →
Priority Claims (1)
FR 1752867 · Apr 3, 2017 · national
Continuity (1)
Related Publication 20200188916A1 · Jun 18, 2020