IP Library › Granted Patent US 10,752,644
Granted Patent B2
US 10,752,644 · App. 16/515,788 · Granted Aug 25, 2020

Modulators of Sestrin-GATOR2 interaction and uses thereof

Inventors: Kristina Michelle Fetalvero (Boston, MA); Sridhar Narayan (Belmont, MA); David John O'Neill (Arlington, MA); Eddine Saiah (Brookline, MA); Shomit Sengupta (Belmont, MA)
Assignee: NAVITOR PHARMACEUTICALS, INC.
C07F7/081A61K31/197A61K31/198A61K31/221A61K31/223A61K31/275A61K31/341A61K31/41A61K31/695A61K38/00A61K45/06C07C229/12C07C229/14C07C229/18C07C229/20C07C229/28C07C233/07C07C233/40C07C233/47C07C233/49C07C233/51C07C233/63C07C233/83C07C237/06C07C237/12C07C237/30C07C255/61C07C261/04C07C311/06C07C311/10C07C311/13C07C311/14C07C311/19C07C311/51C07D257/04C07D307/33C07C2601/04C07C2601/08C07C2601/14
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Quick Facts
Patent No.
US 10,752,644
App. No.
16/515,788
Granted
Aug 25, 2020
Kind
B2
Abstract

The present invention provides compounds, compositions thereof, and methods of using the same.

Claims (4)

1. A compound selected from:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutically acceptable composition comprising the compound according to claim 1 , and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

3. A method for treating depression in a patient in need thereof, comprising a step of administering to said patient the composition of claim 2 .

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 6, 2026
From: NAVITOR PHARMACEUTICALS, INC.
To: SUPERNUS PHARMACEUTICALS, INC.
Reel/Frame 075552/0122 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 5, 2019
From: FETALVERO, KRISTINA MICHELLE; NARAYAN, SRIDHAR; O'NEILL, DAVID JOHN; SAIAH, EDDINE; SENGUPTA, SHOMIT
To: NAVITOR PHARMACEUTICALS, INC.
Reel/Frame 049955/0297 →
Continuity (5)
Continuation 15974734 · May 9, 2018
Continuation 15331362 · Oct 21, 2016
Provisional Application 62336219 · May 13, 2016
Provisional Application 62245553 · Oct 23, 2015
Related Publication 20200079800A1 · Mar 12, 2020
Cited By (4)
US 12,252,456 US 12,378,263 US 12,427,130 US 12,465,583