IP Library Granted Patent US 11,008,345
Granted Patent B2
US 11,008,345 · App. 16/526,248 · Granted May 18, 2021

Boron-containing small molecules

Inventors: Vincent S. Hernandez (Watsonville, CA); Charles Ding (San Mateo, CA); Jacob J. Plattner (Berkeley, CA); Michael Richard Kevin Alley (Santa Clara, CA); Fernando Rock (Los Altos, CA); Suoming Zhang (San Mateo, CA); Eric Easom (Mountain View, CA); Xianfeng Li (Cupertino, CA); Ding Zhou (Shanghai, CN)
Assignee: Anacor Pharmaceuticals, Inc.
C07F5/025
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Quick Facts
Patent No.
US 11,008,345
App. No.
16/526,248
Granted
May 18, 2021
Kind
B2
Abstract

This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.

Claims (9)

1. A compound having a structure which is:

wherein R 3 is —CH 2 NH 2 ;

R 4 is selected from the group consisting of halogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl, methoxy, ethoxy, propoxy, isopropoxy, butoxy, isobutoxy, and sec-butoxy;

Y is O; and

R 5 is

wherein a is 2, 3 or 4;

R 10 and R 11 is H; and

R 12 is selected from the group consisting of H, OH, NH 2 , methyl, ethyl, —NHS(O) 2 CH 3 , cyano, —NHC(O)CH 3 , —NHC(O)NHCH 2 CH 3 , —C(O)NH 2 , —C(O)OH, 4-(methoxy)phenyl, benzyl, benzoxy, —NHC(O)OCH 2 Ph, —C(O)NHCH 2 CH 2 OH and —C(NH 2 )(NH);

or a salt, hydrate or solvate thereof.

Assignments (2)
CHANGE OF NAME Recorded Jan 11, 2024
From: ANACOR PHARMACEUTICALS, INC.
To: ANACOR PHARMACEUTICALS, LLC
Reel/Frame 066285/0934 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 30, 2019
From: HERNANDEZ, VINCENT S.; DING, CHARLES; PLATTNER, JACOB J.; ALLEY, MICHAEL RICHARD KEVIN; ROCK, FERNANDO; ZHANG, SUOMING; EASOM, ERIC; LI, XIANFENG; ZHOU, DING
To: ANACOR PHARMACEUTICALS, INC.
Reel/Frame 049904/0955 →
Continuity (5)
Division 15685846 · Aug 24, 2017
Division 14221637 · Mar 21, 2014
Continuation 13227444 · Sep 7, 2011
Provisional Application 61380596 · Sep 7, 2010
Related Publication 20190345173A1 · Nov 14, 2019