IP Library › Granted Patent US 10,584,131
Granted Patent B2
US 10,584,131 · App. 16/530,274 · Granted Mar 10, 2020

Heteroaromatic NMDA receptor modulators and uses thereof

Inventors: David R. Anderson (Salem, CT); Robert A. Volkmann (Mystic, CT); Gregg F. Keaney (Lexington, MA); Steven C. Leiser (Valley Cottage, NY); Sam Malekiani (Watertown, MA); Timothy Piser (Wilmington, DE)
Assignee: Cadent Therapeutics, Inc.
C07D487/04
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Quick Facts
Patent No.
US 10,584,131
App. No.
16/530,274
Granted
Mar 10, 2020
Kind
B2
Abstract

Provided is 5-(3-chloro-4-fluorophenyl)-7-cyclopropyl-3-(2-(3-fluoro-3-methylazetidin-1-yl)-2-oxoethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one and pharmaceutically acceptable salts thereof, and their uses in the treatment of psychiatric, neurological, and neurodevelopmental disorders, as well as diseases of the nervous system.

Claims (4)

1. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2023
From: CADENT THERAPEUTICS, INC.
To: NOVARTIS AG
Reel/Frame 063077/0166 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 6, 2019
From: ANDERSON, DAVID R.; VOLKMANN, ROBERT A.; KEANEY, GREGG F.; LEISER, STEVEN C.; MALEKIANI, SAM; PISER, TIMOTHY
To: CADENT THERAPEUTICS, INC.
Reel/Frame 049973/0720 →
Continuity (2)
Provisional Application 62714100 · Aug 3, 2018
Related Publication 20200039987A1 · Feb 6, 2020
Cited By (1)
US 12,358,929