IP Library Granted Patent US 11,723,804
Granted Patent B2
US 11,723,804 · App. 16/532,436 · Granted Aug 15, 2023

Device and method for reducing intraocular pressure

Inventors: Lucinda J. Camras (Durham, NC); Rand Allingham (Durham, NC); Bruce Klitzman (Durham, NC); Sanjay Asrani (Chapel Hill, NC)
Assignee: Alievio, Inc.
A61F9/00781A61F2250/0024A61F2250/0051
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Quick Facts
Patent No.
US 11,723,804
App. No.
16/532,436
Granted
Aug 15, 2023
Kind
B2
Abstract

An apparatus is provided for draining aqueous humor from an eye for reducing intraocular pressure. The draining apparatus comprises a tube defining a passage for fluid flow between an inlet end and an outlet end. An outlet assembly contacts the conjunctival layer externally of the eyeball. The outlet assembly comprises a housing in fluid communication with the outlet end of the tube and having an aperture for allowing egress of aqueous humor onto the external ocular surface. A resistive component is disposed in the housing for providing resistance to a flow of aqueous humor. A pair of tabs project outwardly and are adapted to be disposed subconjunctivally for securing the draining apparatus relative to the eyeball.

Claims (20)

1. An apparatus for draining aqueous humor from an eye for reducing intraocular pressure, the apparatus comprising:

a tube extending between an inlet end and an outlet end, the tube defining a passage for a fluid to flow from the inlet end to the outlet end;

a housing defining a cavity in fluid communication with the outlet end of the tube, the cavity configured to receive the fluid from the tube, the housing including an opening configured to allow the fluid to flow out from the cavity to an external area;

a filtration element disposed in a portion of the cavity of the housing; and

a removable cartridge, wherein the fluid flows through the filter and the removable cartridge, the removable cartridge being configured to at least one of provide a selected resistance to the fluid to allow for non-invasive intraocular pressure adjustment or prevent bio-fouling or clogging,

wherein the cavity of the housing includes an inlet, and the filter substantially closes the inlet of the cavity.

2. The apparatus of claim 1 , wherein the removable cartridge is configured to be removable via the opening of the housing.

3. The apparatus of claim 1 , wherein the filtration element is disposed upstream of the removable cartridge such that the fluid flows from the tube to the filter and then flows from the filter to the removable cartridge.

4. The apparatus of claim 1 , wherein the removable cartridge includes an agent that prevents the bio-fouling or the clogging.

5. The apparatus of claim 1 , wherein the removable cartridge is configured to be removed from the cavity while the filter remains in the cavity.

6. The apparatus of claim 1 , wherein the housing includes a flange and the filter is sealed against the flange to substantially close the inlet of the cavity.

7. The apparatus of claim 1 , wherein the filtration element includes a plurality of pores having a plurality of respective pore sizes.

8. The apparatus of claim 7 , wherein the plurality of pores are arranged in the filtration element in order of decreasing or increasing size.

9. The apparatus of claim 1 , wherein the opening in the housing forms a one-way valve that allows the fluid to flow out from the cavity, the one-way valve configured to open in response to a pressure from the flow of the fluid.

10. The apparatus of claim 9 , wherein the one-way valve includes an elongated slit.

11. The apparatus of claim 1 , the removable cartridge is formed from an expandable material that seals the removable cartridge in the cavity of the housing.

12. The apparatus of claim 1 , wherein the cartridge is disposed at an outflow from the housing.

13. The apparatus of claim 12 , wherein the removable cartridge is formed from an expandable material that seals the removable cartridge at the outflow from the housing.

14. The apparatus of claim 1 , wherein the cartridge is removable via an outflow from the housing.

15. The apparatus of claim 1 , wherein the removable cartridge is replaceable with another removable cartridge to provide a different resistance to the fluid.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2023
From: CAMRAS, LUCINDA J.; ALLINGHAM, R. RAND; KLITZMAN, BRUCE; ASRANI, SANJAY
To: CAMRAS VISION, INC.
Reel/Frame 062563/0283 →
CHANGE OF NAME Recorded Feb 1, 2023
From: CAMRAS VISION, INC.
To: ALIEVIO, INC.
Reel/Frame 062609/0681 →
Continuity (3)
Continuation 16043099 · Jul 23, 2018
Continuation 14473228 · Aug 29, 2014
Related Publication 20190358086A1 · Nov 28, 2019