IP Library › Granted Patent US 11,908,584
Granted Patent B2
US 11,908,584 · App. 16/541,621 · Granted Feb 20, 2024

Methods and systems for modeling a necrotized tissue volume in an ablation procedure

Inventor: Andrea Borsic (Turin, IT)
Assignee: NE Scientific, LLC
G16H50/50A61B34/10G16H20/40G16H30/40A61B2018/00577
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,908,584
App. No.
16/541,621
Granted
Feb 20, 2024
Kind
B2
Abstract

A system for modeling a necrotized tissue volume in an ablation procedure includes a radiology workstation designed and configured to provide a computer model of a volume of human tissue based on corporeal image data, simulate an ablation site in the computer model, detect, in the computer model, at least a preferential pathway for heated vapor produced due to ablation of the tissue, wherein the at least a preferential pathway intersects the ablation site, determine a proportion of vapor escaping to the at least a preferential pathway during an ablation procedure, determiner a heat distribution at the ablation site as a function of the distribution of vapor, and generate a simulation of a necrotized tissue volume in the volume of tissue, wherein the simulation of the necrotized tissue volume represents a volume of tissue necrotized by heat during an ablation procedure performed at the ablation site.

Claims (41)

1. A method of modeling a necrotized tissue volume in an ablation procedure, the method comprising:

providing, at a radiology workstation, a computer model of a volume of human tissue;

simulating, by the radiology workstation, an ablation site in the computer model;

detecting, by the radiology workstation and in the computer model, at least a preferential pathway for heated vapor produced due to ablation of the tissue, wherein the at least a preferential pathway intersects the ablation site;

determining, by the radiology workstation, a proportion of vapor escaping to the at least a preferential pathway during an ablation procedure;

determining, by the radiology workstation, a heat distribution at the ablation site as a function of the distribution of vapor; and

generating, by the radiology workstation, a simulation of a necrotized tissue volume in the volume of human tissue, wherein the simulation of the necrotized tissue volume represents a volume of tissue necrotized by heat during an ablation procedure performed at the ablation site.

2. The method of claim 1 , wherein providing the computer model further comprises generating the computer model.

3. The method of claim 2 , wherein generating the computer model further comprises generating the computer model from an image of the volume of human tissue.

4. The method of claim 2 , wherein generating the computer model further comprises registering a virtual model of an organ over an image of the volume of human tissue.

5. The method of claim 1 , wherein simulating the ablation site further comprises simulating a probe insertion.

6. The method of claim 1 , wherein detecting the at least a preferential pathway further comprises detecting, in a virtual model of an organ, a pathway that intersects the ablation site.

7. The method of claim 1 , wherein detecting the at least a preferential pathway further comprises detecting a probe insertion pathway.

8. The method of claim 1 , wherein detecting the at least a preferential pathway further comprises:

introducing an image enhancement substance into the ablation site;

capturing an image of the ablation site with the image enhancement substance; and

detecting the at least a preferential pathway as a function of the image of the ablation site.

9. The method of claim 1 , wherein determining the distribution of vapor to the at least a preferential pathway further comprises:

determining a flow rate of vapor into the at least a preferential pathway; and

determining the distribution of vapor to the at least a preferential pathway as a function of the flow rate.

10. The method of claim 9 , wherein determining the distribution of vapor as a function of the flow rate further comprises:

determining a rate of vapor generation;

comparing the flow rate to the rate of vapor generation; and

determining the distribution of vapor to the at least a preferential pathway as a function of the comparison.

11. The method of claim 1 , wherein determining the distribution of vapor to the at least a preferential pathway further comprises:

deriving a surface area of the at least a preferential pathway; and

determining the distribution of vapor as a function of the surface area.

12. The method of claim 1 , wherein determining the distribution of vapor to the at least a preferential pathway further comprises:

deriving a volume of the at least a preferential pathway; and

determining the distribution of vapor as a function of the volume.

13. The method of claim 1 , wherein determining the heat distribution at the ablation site further comprises:

identifying a proportion of heat converted to vapor; and

determining the heat distribution at the ablation site as a function of the proportion of the heat converted to vapor and the distribution of vapor to the at least a preferential pathway.

14. The method of claim 13 further comprising calculating a distribution of heat transferred to the tissue by the vapor.

15. The method of claim 1 , wherein generating the simulation of the necrotized tissue volume further comprises simulating a primary ablation volume as a function of heat present at the ablation site.

16. The method of claim 1 , wherein generating the simulation of the necrotized tissue volume further comprises simulating necrotized tissue along the at least a preferential pathway.

17. The method of claim 1 further comprising comparing a simulated volume to a volume of tissue intended to be necrotized.

18. A system for modeling a necrotized tissue volume in an ablation procedure, the system comprising:

an radiology workstation, wherein the radiology workstation is designed and configured to provide a computer model of a volume of human tissue based on corporeal image data, simulate an ablation site in the computer model, detect, in the computer model, at least a preferential pathway for heated vapor produced due to ablation of the tissue, wherein the at least a preferential pathway intersects the ablation site, determine a proportion of vapor escaping to the at least a preferential pathway during an ablation procedure, determiner a heat distribution at the ablation site as a function of the distribution of vapor, and generate a simulation of a necrotized tissue volume in the volume of human tissue, wherein the simulation of the necrotized tissue volume represents a volume of tissue necrotized by heat during an ablation procedure performed at the ablation site.

19. The system of claim 14 further comprising a radiological machine in communication with the radiology workstation.

20. The system of claim 14 further comprising an image-guided surgical suite in communication with the radiology workstation.

Assignments (2)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE'S NAME PREVIOUSLY RECORDED AT REEL: FRAME: . ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNEMNT. Recorded May 10, 2023
From: BORSIC, ANDREA
To: NE SCIENTIFIC, LLC
Reel/Frame 063590/0752 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 3, 2019
From: BORSIC, ANDREA
To: NE SCIENTIFIC
Reel/Frame 050247/0812 →
Continuity (2)
Continuation In Part 15595737 · May 15, 2017
Related Publication 20190371474A1 · Dec 5, 2019