IP Library › Granted Patent US 12,290,456
Granted Patent B2
US 12,290,456 · App. 16/546,901 · Granted May 6, 2025

Prosthetic cardiac valve devices, systems, and methods

Inventors: Claudio Argento (Felton, CA); Andrew Backus (Santa Cruz, CA); Alice Yang (Campbell, CA)
Assignee: Shifamed Holdings, LLC
A61F2/88A61F2/2418A61F2/2433A61F2220/0008A61F2230/0004A61F2230/0067A61F2230/0091A61F2250/001
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Quick Facts
Patent No.
US 12,290,456
App. No.
16/546,901
Granted
May 6, 2025
Kind
B2
Abstract

A heart valve prosthesis for replacing a diseased native valve in a patient. The valve prosthesis includes a compressible and expandable frame structure and an anchor connected to an outer periphery of the frame structure. The anchor comprises a helical wire having a free end. The valve may further include a valve segment mounted within the frame structure and expanded with the frame structure. The frame structure may be configured for receiving a valve segment.

Claims (25)

1. A heart valve prosthesis for replacing a diseased native valve in a heart of a patient, the valve prosthesis comprising:

a compressible and expandable frame structure having a frame axis;

a valve segment disposed within the frame structure, the valve segment comprising a biocompatible one-way valve; and

a compressible and expandable anchor permanently attached to and configured to encircle an outer periphery of the frame structure, wherein the anchor comprises a spiral wire and a free end, the free end having a larger radius of curvature than the spiral wire;

wherein the heart valve prosthesis has an anchoring configuration in which the anchor is in an expanded state, the frame structure is in a collapsed state, and the frame axis is centrally located within the spiral wire;

wherein when heart valve prosthesis is in the anchoring configuration, rotation of the spiral wire is configured to guide the frame structure into the native valve.

2. The valve prosthesis of claim 1 , wherein the free end is configured to guide the spiral wire through a commissure of a native valve of a patient.

3. The valve prosthesis of claim 1 , wherein the free end comprises an atraumatic tip.

4. The valve prosthesis of claim 3 , wherein the free end comprises a ball tip.

5. The valve prosthesis of claim 1 , wherein the free end is configured for piercing tissue.

6. The valve prosthesis of claim 1 , wherein the frame structure is configured for expanding within a native valve of a patient.

7. The valve prosthesis of claim 1 , wherein the frame structure has a compressed state sized and dimensioned for percutaneous insertion and an expanded state sized and dimensioned for implantation in a native valve of a patient.

8. The valve prosthesis of claim 1 , wherein the frame structure comprises first and second opposite ends, the first end configured to extend above a native valve and the second end configured to extend below the native valve when the valve prosthesis is positioned across the native valve.

9. The valve prosthesis of claim 1 , wherein the frame structure comprises an expandable stent.

10. The valve prosthesis of claim 1 , wherein the frame structure comprises a generally tubular expanded shape.

11. The valve prosthesis of claim 1 , wherein the frame structure comprises an expanded outer periphery and a compressed outer periphery when subject to an external radial force, wherein the compressed outer periphery is smaller in diameter than the expanded outer periphery.

12. The valve prosthesis of claim 1 , wherein the frame structure is self-expanding.

13. The valve prosthesis of claim 1 , wherein the valve segment comprises at least one leaflet having an inner layer and an outer layer, and wherein the frame structure is attached to the outer layer at one or more ends of the frame structure.

14. The valve prosthesis of claim 1 , wherein the valve segment comprises a plurality of leaflets.

15. The valve prosthesis of claim 14 , wherein the valve segment comprises two leaflets.

16. The valve prosthesis of claim 1 , wherein the anchor and the frame structure are adapted to be independently and separately expanded.

17. The valve prosthesis of claim 1 , wherein the spiral wire is fixedly connected to the frame structure only at one end of the spiral wire.

18. The valve prosthesis of claim 1 , wherein the free end is configured to capture chordae tendineae of the native valve when the anchor is rotated within the heart in the anchoring configuration.

19. The valve prosthesis of claim 1 , wherein in the anchoring configuration, the frame axis is aligned with a central axis of the anchor.

20. The valve prosthesis of claim 1 , wherein the anchor is configured to concentrically encircle the outer periphery of the frame structure.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 29, 2025
From: SHIFAMED HOLDINGS, LLC
To: TIOGA CARDIOVASCULAR, INC.
Reel/Frame 073425/0381 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2023
From: ARGENTO, CLAUDIO; BACKUS, ANDREW; YANG, ALICE
To: SHIFAMED HOLDINGS, LLC
Reel/Frame 063870/0816 →
Continuity (2)
Provisional Application 62720853 · Aug 21, 2018
Related Publication 20200060852A1 · Feb 27, 2020
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