Repositionable heart valve
A replacement heart valve assembly including an expandable anchor having a skirt region, a lip region, and a groove region therebetween and a replacement valve disposed within the expandable anchor and engaged with the groove region of the expandable anchor.
1. A replacement heart valve assembly comprising:
an expandable anchor having a delivery configuration and a fully deployed configuration, the expandable anchor comprising a skirt region, a lip region, and a groove region therebetween;
in the delivery configuration, the expandable anchor having a first diameter and a first length and in the fully deployed configuration having a second diameter and a second length, wherein the first length is greater than the second length and the second diameter is greater than the first diameter;
a replacement valve disposed within the expandable anchor, the replacement valve including posts and hoop regions, the posts and hoop regions having a collapsed delivery configuration and an expanded deployed configuration in which the hoop regions are adapted to engage the groove region of the expandable anchor in the fully deployed configuration thereof;
the lip region of the expandable anchor is configured and adapted to expand radially outward relative to the groove region while transitioning from the delivery configuration to the fully deployed configuration to engage native valve leaflets and to provide positive registration and ensure accurate placement of the expandable anchor relative to a valve annulus during deployment.
2. The replacement heart valve assembly of claim 1 , wherein the posts and hoop regions form an expandable frame.
3. The replacement heart valve assembly of claim 2 , wherein the expandable frame is formed from a continuous piece of material.
4. The replacement heart valve assembly of claim 3 , wherein the continuous piece of material is balloon expandable.
5. The replacement heart valve assembly of claim 3 , wherein the continuous piece of material is self-expanding.
6. The replacement heart valve assembly of claim 5 , wherein the expandable anchor is balloon expandable.
7. The replacement heart valve assembly of claim 1 , wherein the expandable anchor is a self-expanding expandable anchor.
8. The replacement heart valve assembly of claim 7 , wherein the self-expanding expandable anchor is Nitinol.
9. The replacement heart valve assembly of claim 1 , wherein a valve portion of the replacement heart valve assembly comprises a plurality of leaflets.
10. The replacement heart valve assembly of claim 9 , wherein the valve portion of the replacement heart valve assembly comprises three leaflets.
11. The replacement heart valve assembly of claim 9 , wherein the plurality of leaflets comprise a synthetic material.
12. The replacement heart valve assembly of claim 9 , wherein the plurality of leaflets comprise biologic tissue.
13. The replacement heart valve assembly of claim 12 , wherein the biologic tissue is porcine tissue.
14. The replacement heart valve assembly of claim 12 , wherein the biologic tissue is bovine tissue.
15. The replacement heart valve assembly of claim 10 , wherein in cross-section, the groove region has a concave inner surface and a convex outer surface.
16. The replacement heart valve assembly of claim 15 , wherein the groove region is C-shaped in cross-section.
17. The replacement heart valve assembly of claim 15 , wherein the groove region is U-shaped in cross-section.
18. The replacement heart valve assembly of claim 1 , wherein the skirt region of the expandable anchor is located at an in-flow end of the replacement heart valve assembly.
19. The replacement heart valve assembly of claim 15 , wherein an outer surface of the skirt region faces toward the groove region in the fully deployed configuration.