Therapy delivery devices and methods for non-damaging neural tissue conduction block
Devices and methods for blocking signal transmission through neural tissue. One step of a method includes placing a therapy delivery device into electrical communication with the neural tissue. The therapy delivery device includes an electrode contact having a high charge capacity material. A multi-phase direct current (DC) can be applied to the neural tissue without damaging the neural tissue. The multi-phase DC includes a cathodic DC phase and anodic DC phase that collectively produce a neural block and reduce the charge delivered by the therapy delivery device. The DC delivery can be combined with high frequency alternating current (HFAC) block to produce a system that provides effective, safe, long term block without inducing an onset response.
1. An electrode, comprising:
at least one contact configured to be in electrical communication with neural tissue and further configured to deliver a therapy signal comprising a current configured to deliver a charge to the neural tissue,
wherein the at least one contact comprises a high charge capacity material that is configured to limit formation of irreversible reaction products when the current of the therapy signal delivers the charge to the neural tissue, and
wherein the charge is 100 μC or more.
2. The electrode of claim 1 , wherein the at least one contact is fabricated of the high charge capacity material.
3. The electrode of claim 1 , wherein the at least one contact comprises a base body that is at least partially coated with the high charge capacity material.
4. The electrode of claim 1 , wherein the high charge capacity material comprises platinum black, iridium oxide, titanium nitride, tantalum, poly(ethylenedioxythiophene), or a combination thereof.
5. The electrode of claim 1 , wherein the at least one contact is monopolar.
6. The electrode of claim 1 , wherein the at least one contact has a Q value in the range of 2.9 mC to 5.6 mC.
7. An electrode, comprising:
at least one contact configured to be in electrical communication with electrically excitable tissue and further configured to deliver a therapy signal comprising a current configured to deliver a charge to the excitable tissue,
wherein the at least one contact comprises a high charge capacity material that is configured to limit formation of irreversible reaction products when the current of the therapy signal delivers the charge to the excitable tissue, and
wherein the charge is 100 μC or more .
8. The electrode of claim 7 , wherein the at least one contact has a Q value in the range of 2.9 mC to 5.6 mC.
9. A method comprising placing at least one contact of an electrode in electrical communication with excitable tissue; and delivering a therapy signal through the at least one contact to the excitable tissue to provide a charge to the excitable tissue; wherein the at least one contact comprises a high charge capacity material that limits formation of irreversible reaction products when the therapy signal delivers the charge to the excitable tissue, and wherein the excitable tissue comprises spinal nerves and wherein the charge is 100 μC or more.
10. The method of claim 9 , wherein the excitable tissue comprises brain tissue.
11. The method of claim 9 , wherein the excitable tissue comprises ganglia.
12. The method of claim 9 , further comprising blocking signal transmission through at least a portion of the neural tissue based on the application of the therapy signal.
13. The method of claim 9 , wherein the therapy signal comprises a current that delivers a charge of 100 μC or more to the neural tissue.
14. The method of claim 9 , wherein the at least one contact has a Q value in the range of 2.9 mC to 5.6 mC.