Nutritional supplements and therapeutic compositions comprising probiotics
Disclosed herein are therapeutic compositions and nutritional supplements comprising probiotic mixtures and sleep-support ingredients, and a method of treating digestive discomfort and sleep problems comprising administering an effective amount of a therapeutic composition comprising a probiotic component and a sleep support component. According to embodiments, therapeutic compositions for improved digestion are provided comprising: a probiotic component, comprising: at least one of Lactobacillus acidophilus, Bifidobacterium bifidum, Bifidobacterium animalis, Lactobacillus rhamnosus , and Lactobacilus paracasei ; and a sleep support component, comprising: at least one of gamma-aminobutyric acid (GABA), valerian root extract, and melatonin. The therapeutic compositions are effective in treating both sleep disorders and digestive discomfort.
1. A therapeutic composition for improving digestion consisting of:
a probiotic component consisting of:
Lactobacillus acidophilus, Bifidobacterium bifidum, Bifidobacterium animalis, Lactobacillus rhamnosus , and Lactobacilus paracasei;
a sleep support component consisting of:
gamma-aminobutyric acid (GABA), valerian root extract, and melatonin; and
one or more excipients.
2. The therapeutic composition according to claim 1 , wherein the excipient is at least one of microcrystalline cellulose, silica, magnesium stearate, or a combination thereof.
3. The therapeutic composition of claim 1 , wherein the excipient consists of:
microcrystalline cellulose,
silica, and
magnesium stearate.
4. The therapeutic composition of claim 1 , consisting of:
at least 0.05 B CFU/g of the probiotic component,
at least 10 mg of gamma-aminobutyric acid (GABA),
at least 1 mg of valerian root extract, and
at least 0.1 mg of melatonin; and
one or more excipients.
5. The therapeutic composition of claim 1 , consisting of:
from about 0.05 B CFU/g to about 50 B CFU/g of the probiotic component,
from about 10 mg to about 500 mg of gamma-aminobutyric acid (GABA),
from about 1 mg to about 200 mg of valerian root extract,
from about 0.1 mg to about 10 mg of melatonin; and
one or more excipients.
6. The therapeutic composition of claim 1 , consisting of:
about 27 B CFU/g of the probiotic component,
about 100 mg of gamma-aminobutyric acid (GABA),
about 50 mg of valerian root extract,
about 1.50 mg of melatonin; and
one or more excipients.
7. The composition of claim 1 in a capsule.
8. A composition for improving digestion consisting of:
a culture blend consisting of:
Lactobacillus acidophilus (ATCC SD6865),
Lactobacillus acidophilus (ATCC SD6866),
Bifidobacterium bifidum (ATCC SD6869), and
Bifidobacterium animalis subsp. lactis (ATCC SD6870);
a microbiome blend consisting of:
Lactobacillus rhamnosus (IMC 501), and
Lactobacillus paracasei (IMC 502);
gamma-aminobutyric acid (GABA);
valerian root extract;
melatonin; and
one or more excipients.
9. The composition of claim 8 , wherein the one or more excipients consists of:
microcrystalline cellulose,
silica, and
magnesium stearate.
10. The composition of claim 8 , consisting of:
at least 1 B CFU/g of the culture blend,
at least 0.1 B CFU/g of the microbiome blend,
at least 10 mg of gamma-aminobutyric acid (GABA),
at least 1 mg of valerian root extract,
at least 0.2 mg melatonin, and
one or more excipients.
11. The composition of claim 8 , consisting of:
from about 1 B CFU/g to about 50 B CFU/g of the culture blend,
from about 0.1 B CFU/g to about 5 B CFU/g of the microbiome blend,
from about 10 mg to about 500 mg of the gamma-aminobutyric acid (GABA),
from about 1 mg to about 200 mg of the valerian root extract,
from about 0.1 mg to about 10 mg of melatonin; and
one or more excipients.
12. The composition of claim 11 , consisting of:
about 26 B B CFU/g of the culture blend,
about 1 B CFU/g of the microbiome blend,
about 100 mg of the gamma-aminobutyric acid (GABA),
about 50 mg of the valerian root extract,
about 01.50 mg of melatonin; and
one or more excipients.
13. The composition of claim 12 , further comprising wherein the one or more excipients consists of:
about 39 mg microcrystalline cellulose,
about 6 mg silica, and
about 4 mg magnesium stearate.
14. A method for improving digestion, comprising administering to an individual an effective dose of a composition consisting of:
Lactobacillus acidophilus,
Bifidobacterium bifidum,
Bifidobacterium animalis subsp. lactis,
Lactobacillus rhamnosus,
Lactobacillus paracasei,
gamma-aminobutyric acid (GABA),
valerian root extract,
melatonin; and
one or more excipients.
15. The method of claim 14 , wherein the composition promotes sleep.
16. The method of claim 14 , wherein the composition consists of:
about 26 B CFU/g of a culture blend consisting of:
Lactobacillus acidophilus (ATCC SD6865),
Lactobacillus acidophilus (ATCC SD6866),
Bifidobacterium bifidum (ATCC SD6869), and
Bifidobacterium animalis subsp. lactis (ATCC SD6870);
about 1 B CFU/g of a microbiome blend consisting of:
Lactobacillus rhamnosus (IMC 501), and
Lactobacillus paracasei (IMC 502);
about 100 mg of the gamma-aminobutyric acid (GABA);
about 50 mg of the valerian root extract;
about 1.50 mg of melatonin; and
one or more excipients.