IP Library › Granted Patent US 11,077,163
Granted Patent B2
US 11,077,163 · App. 16/582,014 · Granted Aug 3, 2021

Peptide for treating ocular diseases and composition for treating ocular diseases comprising same

Inventor: Sang Jae Kim (Seoul, KR)
Assignee: GemVax & KAEL Co., Ltd.
A61K38/02A61K38/10A61K38/17C07K1/045C07K1/061C07K1/10C07K1/16
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Quick Facts
Patent No.
US 11,077,163
App. No.
16/582,014
Granted
Aug 3, 2021
Kind
B2
Abstract

A pharmaceutical composition for preventing or treating ophthalmopathy is described. More particularly, a composition comprising a peptide derived from telomerase and being effective in treating and preventing ophthalmopathy is described. The peptide derived from telomerase, a peptide having a sequence 80% identical to the sequence thereof, or a peptide as a fragment thereof is superiorly effective in treating ophthalmopathy.

Claims (14)

1. A method of inhibiting choroidal neovascularization, comprising:

administering to a subject in need thereof an effective amount of an isolated peptide consisting of the amino acid sequence of SEQ ID NO: 1.

2. The method of claim 1 , wherein the peptide is administered at a daily dose of 10 ng/kg to 10 mg/kg.

3. The method of claim 1 , wherein the peptide is administered at a daily dose of 2 μg/kg to 50 μg/kg.

4. The method of claim 1 , wherein the peptide is administered 1 to 3 times a day.

5. A method of inhibiting choroidal neovascularization, comprising:

administering to a subject in need thereof a composition comprising an effective amount of an isolated peptide consisting of the amino acid sequence of SEQ ID NO: 1.

6. The method of claim 5 , wherein the composition further comprises a pharmaceutically acceptable excipient and an additive.

7. The method of claim 5 , wherein the composition is a food composition.

8. The method of claim 5 , wherein the composition comprises 0.01 g/L to 1 kg/L of the peptide.

9. The method of claim 5 , wherein the composition comprises 1 g/L to 10 g/L of the peptide.

10. The method of claim 5 , wherein the peptide is administered at a daily dose of 10 ng/kg to 10 mg/kg.

11. The method of claim 5 , wherein the peptide is administered at a daily dose of 2 μg/kg to 50 μg/kg.

12. The method of claim 5 , wherein the peptide is administered 1 to 3 times a day.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2023
From: GEMVAX & KAEL CO. LTD.
To: GEMVAX & KAEL CO. LTD.; KIM, SANG JAE
Reel/Frame 065471/0754 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 11, 2021
From: KIM, SANG JAE
To: GEMVAX & KAEL CO., LTD.
Reel/Frame 055563/0506 →
Continuity (2)
Division 15539396
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