Devices and methods for treating craniofacial pain
Some implementations provide a method for treating craniofacial pain in a patient, the method including: placing a wirelessly powered passive device through an opening into a target site in a head or neck region of the patient's body, the wirelessly powered passive device configured to receive an input signal non-inductively from an external antenna; positioning the wirelessly powered passive device adjacent to or near a nerve at the target site; and causing neural modulation to the nerve through one or more electrodes on the wirelessly powered passive device.
1. A stylet device for delivering a battery-less implantable wireless stimulator device, the stylet device comprising:
a proximal end that includes a handle and a locking feature;
a body sized to fit inside an introducer device, wherein the introducer device is separate from the stylet device;
a shaft inside the body, wherein the handle is coupled to a plunger movable inside the shaft; and
a distal end that includes a mating feature capable of mating with the battery-less implantable wireless stimulator device for treating craniofacial pain in a patient,
wherein the plunger is configured to slide within the shaft toward the proximal end of the stylet device to create a force sufficient for the mating feature to mate with the battery-less implantable wireless stimulator device such that, when the stylet device is advanced through the introducer device at a target site in a head or neck region of the patient, the battery-less implantable wireless stimulator device enters the target site, and
wherein the plunger is further configured to slide within the shaft toward the distal end to dismantle the force at the distal end such that the battery-less implantable wireless stimulator device becomes implanted at the target site to apply neural modulation to a surrounding nerve.
2. The stylet device of claim 1 , wherein when the handle is set to engage the locking feature, the force is created at the distal end of the stylet device, and wherein when the handle is set to disengage the locking feature, the force is dismantled at the distal end of the stylet device.
3. The stylet device of claim 1 , wherein the distal end further includes a chamber bordered by a distal tip of the plunger and a proximal tip of the mating feature.
4. The stylet device of claim 1 , wherein the plunger is configured to slide within the shaft toward the proximal end of the stylet device to generate negative air pressure such that the force is created as a suction force at the distal end of the stylet device.
5. The stylet device of claim 4 , wherein when the handle is set to disengage the locking feature, the plunger is released inside the shaft such that the suction force is removed at the distal end of the stylet device.
6. The stylet device of claim 1 , wherein the plunger is configured to slide inside the shaft to more than one position to generate variable negative air pressure such that variable suction forces are created at the distal end of the stylet device.
7. The stylet device of claim 1 , wherein the body is capable of fitting inside an introducer with a size of 13 gauge or smaller to implant the battery-less implantable wireless stimulator device at the target site.
8. The stylet device of claim 7 , wherein the body is between about 50 mm and 170 mm in length.
9. The stylet device of claim 7 , wherein the target site comprises: an occipital nerve or branches thereof, a trochlear nerve or branches thereof, a vagus nerve or branches thereof, a trigeminal nerve or branches thereof, a glossopharyngeal nerve or branches thereof, a mandibular nerve or branches thereof, an alveolar nerve or branches thereof, a lingual nerve or branches thereof, a maxillary nerve or branches thereof, a ciliary nerve or branches thereof, a sphenopalatine ganglion or branches thereof, and a supratrochlear nerve or branches thereof.
10. A system comprising:
a battery-less implantable wireless stimulator device for treating craniofacial pain; and
a stylet device that includes:
a proximal end that includes a handle and a locking feature;
a body sized to fit inside an introducer device, wherein the introducer device is separate from the system;
a shaft inside the body, wherein the handle is coupled to a plunger movable inside the shaft and
a distal end that includes a mating feature capable of mating with the battery-less implantable wireless stimulator device for implantation in a patient,
wherein the plunger is configured to slide within the shaft toward the proximal end of the stylet device to create a force sufficient for the mating feature to mate with the battery-less implantable wireless stimulator device such that, when the stylet device is advanced through the introducer device at a target site in a head or neck region of the patient, the battery-less implantable wireless stimulator device enters the target site, and
wherein the plunger is further configured to slide within the shaft toward the distal end to dismantle the force at the distal end such that the battery-less implantable wireless stimulator device becomes implanted at the target site to apply neural modulation to a surrounding nerve.
11. The system of claim 10 , wherein when the handle is set to engage the locking feature, the force is created at the distal end of the stylet device, and wherein when the handle is set to disengage the locking feature, the force is dismantled at the distal end of the stylet device.
12. The system of claim 10 , wherein the distal end further includes a chamber bordered by a distal tip of the plunger and a proximal tip of the mating feature.
13. The system of claim 10 , wherein the plunger is configured to slide within the shaft toward the proximal end of the stylet device to generate negative air pressure such that the force is created as a suction force at the distal end of the stylet device.
14. The system of claim 13 , wherein when the handle is set to disengage the locking feature, the plunger is released inside the shaft such that the suction force is removed at the distal end of the stylet device.
15. The system of claim 10 , wherein the plunger is configured to slide inside the shaft to more than one position to generate variable negative air pressure such that variable suction forces are created at the distal end of the stylet device.
16. The system of claim 10 , wherein the body is capable of fitting inside an introducer with a size of 13 gauge or smaller to implant the battery-less implantable wireless stimulator device at the target site.
17. The system of claim 16 , wherein the body is between about 50 mm and 170 mm in length.
18. The system of claim 10 , wherein the battery-less implantable wireless stimulator device comprises:
one or more non-inductive antennas configured to receive electric energy radiated from a source located outside of the patient and through radiative coupling;
an electronic circuit coupled to each of the one or more non-inductive antennas and configured to extract the electric energy received by the one or more non-inductive antennas and generate stimulation currents using the extracted electric energy; and
one or more electrodes coupled to the electronic circuit and configured to apply the stimulation currents to at least one of: an occipital nerve or branches thereof, a trochlear nerve or branches thereof, a vagus nerve or branches thereof, a trigeminal nerve or branches thereof, a glossopharyngeal nerve or branches thereof, a mandibular nerve or branches thereof, an alveolar nerve or branches thereof, a lingual nerve or branches thereof, a maxillary nerve or branches thereof, a ciliary nerve or branches thereof, a sphenopalatine ganglion or branches thereof, and a supratrochlear nerve or branches thereof.