Contact lens with a hydrophilic layer
Embodiments of the technology relate to a contact lens having a core that is covalently coated by a hydrogel layer, and to methods of making such a lens. In one aspect, embodiments provide for a coated contact lens comprising a lens core comprising an outer surface; and a hydrogel layer covalently attached to at least a portion of the outer surface, the hydrogel layer adapted to contact an ophthalmic surface, wherein the hydrogel layer comprises a hydrophilic polymer population having a first PEG species and a second PEG species, the first PEG species being at least partially cross-linked to the second PEG species.
1. A coated contact lens comprising:
a lens core comprising an outer surface; and
a hydrogel layer covalently attached to at least a portion of the outer surface, the hydrogel layer adapted to contact an ophthalmic surface, wherein the hydrogel layer is formed via a click reaction and comprises:
a hydrophilic polymer population comprising the formula:
wherein:
R1 is polyethylene glycol;
R2 is a second polymer species; and
x is NH, S, or O.
2. The coated contact lens of claim 1 , wherein the second polymer species is polyacrylamide.
3. The coated contact lens of claim 1 , wherein the hydrogel layer is covalently attached to the core by a sulfonyl moiety, a thioether moiety, an amine moiety, or any combination thereof.
4. The coated contact lens of claim 1 , wherein the hydrogel layer comprises a thickness between 0.01 microns and 0.05 microns.
5. The coated contact lens of claim 1 , wherein one or more of the polyethylene glycol and the second polymer species is a branched species having a branch count between two to twelve branch arms.
6. The coated contact lens of claim 1 , wherein one or more of the polyethylene glycol and the second polymer species comprises starred branching.
7. The coated contact lens of claim 1 , wherein the coated contact lens is characterized as comprising an advancing contact angle between 20 degrees to 50 degrees.
8. The coated contact lens of claim 1 , wherein the coated contact lens is characterized as comprising an advancing contact angle between 25 degrees to 35 degrees.
9. The coated contact lens of claim 1 , wherein the hydrogel layer comprises between 80% to 98% water by weight.
10. A coated contact lens comprising:
a lens core comprising an outer surface; and
a hydrogel layer covalently attached to at least a portion of the outer surface, the hydrogel layer adapted to contact an ophthalmic surface, wherein the hydrogel layer is formed via a click reaction and comprises:
a hydrophilic polymer population comprising the formula:
wherein:
R1 is a first polyacrylamide species;
R2 is a second polymer species; and
x is NH, S, or O.
11. The coated contact lens of claim 10 , wherein the second polymer species comprises a second polyacrylamide species.
12. The coated contact lens of claim 10 , the hydrogel layer substantially surrounds the outer surface of the lens core.
13. The coated contact lens of claim 10 , wherein the hydrogel layer comprises a thickness between 0.01 microns and 0.05 microns.
14. The coated contact lens of claim 10 , wherein one or more of the first polyacrylamide species and the second polymer species is a branched species having a branch count between two to twelve branch arms.
15. The coated contact lens of claim 10 , wherein one or more of the first polyacrylamide species and the second polymer species comprises starred branching.
16. The coated contact lens of claim 10 , wherein the coated contact lens is characterized as comprising an advancing contact angle between 20 degrees to 50 degrees.
17. The coated contact lens of claim 10 , wherein the coated contact lens is characterized as comprising an advancing contact angle between 25 degrees to 35 degrees.
18. The coated contact lens of claim 10 , wherein the hydrogel layer comprises between 80% to 98% water by weight.
19. The coated contact lens of claim 10 , wherein the core comprises silicone.