Methods for treating atherosclerosis with gamma-ketoaldehyde scavengers

1. A method of attenuating atherosclerosis, comprising administering to a patient in need thereof a compound of the following formula:

wherein:

R is C;

R 2 is independently H, C 1-6 alkyl, or C 1-6 alkoxy;

R 3 is H, hydroxy, halogen, C 1-6 alkyl, C 1-6 alkoxy, or NO 2 ;

R 4 is H, C 1-6 alkyl, CH 2 C(O)OH or C(O)OH;

R 5 is H, or C 1-6 alkyl;

and a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , wherein the compound is of the following formula:

or a pharmaceutically acceptable salt thereof.

3. The method of claim 1 , wherein the compound is of the following formula:

or a pharmaceutically acceptable salt thereof.

4. The method of claim 1 , wherein the compound is of the following formula:

or a pharmaceutically acceptable salt thereof.

5. The method of claim 1 , wherein the compound is 2-hydroxybenzylamine, methyl-2-hydroxybenzylamine, or ethyl-2-hydroxybenzylamine.