IP Library Granted Patent US 11,253,530
Granted Patent B2
US 11,253,530 · App. 16/611,282 · Granted Feb 22, 2022

Synergistic production of butyrate associated with the complexity of HMOS blend for use in infants or young children for health purposes

Inventors: Florence Rochat (Montreux, CH); Laurent Favre (Carrouge, CH); Norbert Sprenger (Savigny, CH)
Assignee: Societe des Produits Nestle S.A.
A61K31/702A61K9/0056A61K9/0095A61P1/00
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Quick Facts
Patent No.
US 11,253,530
App. No.
16/611,282
Granted
Feb 22, 2022
Kind
B2
Abstract

The present invention relates to a nutritional composition comprising at least three human milk oligosaccharides, for use to increase butyrate production in the digestive tract in an infant or a young child. The production increases with the HMOs blend complexity.

Claims (9)

1. A method to treat a health disorder and/or to promote a health benefit in an infant or a young child in need thereof, the method comprising administering a nutritional composition to the infant or young child, the nutritional composition comprising 2′-fucosyllactose ( 2 ′FL), difucosyllactose (DFL), lacto-N-neotetraose (LNnT), lacto-N-tetraose (LNT), 3′-sialyllactose (3SL) and 6′-sialyllactose (6SL) as the only human milk oligosaccharides in the nutritional composition,

wherein the health disorder is selected from the group consisting of inflammation, allergies, and metabolic health disorders,

and/or wherein the health benefit is selected from the group consisting of gut maturation, gut brain axis connection, and colonic healing.

2. The method of claim 1 , wherein the metabolic health disorders are selected from the group consisting of obesity later in life, type 2 diabetes, and insulin resistance.

3. The method of claim 1 , wherein the colonic healing treats colitis in the infant or young child.

4. The method of claim 1 , wherein a total amount of the 2′FL, the DFL, the LNnT, the LNT, the 3SL and the 6SL is 0.1 wt. % to 10 wt. % of the nutritional composition.

5. The method of claim 1 , wherein a total amount of the 2′FL, the DFL, the LNnT, the LNT, the 3SL and the 6SL is 0.5 wt. % to 7 wt. % of the nutritional composition.

6. The method of claim 1 , wherein a total amount of the 2′FL, the DFL, the LNnT, the LNT, the 3SL and the 6SL is 0.6 wt. % to 1.5 wt. % of the nutritional composition.

7. The method of claim 1 , wherein a total amount of the 2′FL, the DFL, the LNnT, the LNT, the 3SL and the 6SL is 0.8 wt. % to 1.2 wt. % of the nutritional composition.

Assignments (2)
MERGER Recorded Sep 22, 2021
From: NESTEC S.A.
To: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
Reel/Frame 057563/0797 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 22, 2021
From: ROCHAT, FLORENCE; FAVRE, LAURENT; SPRENGER, NORBERT
To: NESTEC S.A.
Reel/Frame 057569/0265 →
Priority Claims (1)
EP 17170064 · May 9, 2017 · regional
Continuity (1)
Related Publication 20200163981A1 · May 28, 2020