System and methods for treating neurovascular compression
The invention is directed to a system and methods for treating neurovascular compression. Certain preferred embodiments of the invention generally comprise an apparatus having an elongated body portion including a proximal anchor element and distal anchor element. The apparatus also may include one or more marker elements to facilitate placement of the apparatus by the user. The apparatus may be configured to permit the user, after insertion and deployment of the apparatus in a blood vessel, to move the blood vessel so that the blood vessel is no longer in contact with and compressing a nerve or other parts of the nervous system.
1. An apparatus configured to change a geometry of a blood vessel in contact with a nerve, the apparatus comprising:
a body portion having a proximal end and a distal end;
an anchor element disposed on at least one of said proximal end and said distal end; and
one or more marker elements disposed on said body portion;
said body portion comprising at least two wires wrapped about one another to form a braided wire, the body portion being sized and shaped to change the geometry of the blood vessel upon insertion of the apparatus into the blood vessel to no longer contact the nerve, and being configured to have a rigidity and a length, the rigidity and length selected based on a length of a curvature in the blood vessel and a diameter of the blood vessel, the rigidity controlled by one or more of the number of wires of the braided wire, a thickness of the wires, and a material of the wires, the rigidity being sufficient to retain the changed geometry of the blood vessel with the apparatus positioned therein and reduce or eliminate blood vessel pulsation.
2. The apparatus of claim 1 , wherein said apparatus is constructed of a biocompatible polymer.
3. The apparatus of claim 1 , wherein said apparatus is constructed of a biocompatible metal selected from the group consisting of nitinol, stainless steel, and cobalt-chromium alloy.
4. The apparatus of claim 1 , wherein said anchor element is constructed of a self-expanding material.
5. The apparatus of claim 1 , wherein said anchor element includes a flared end or open end.
6. The apparatus of claim 1 , wherein said anchor element is disposed on each of said proximal end and said distal end.
7. A method for treating vascular nerve compression comprising:
using a guidewire to position a microcatheter within a blood vessel at a site of the vascular nerve compression;
withdrawing the guidewire from the microcatheter and inserting an apparatus of claim 1 into the microcatheter;
positioning the apparatus at the site of the vascular nerve compression;
withdrawing the microcatheter from the site of vascular nerve compression to deploy the apparatus; and
repositioning the blood vessel using the apparatus to no longer contact a nerve and reduce the vascular nerve compression.
8. The method of claim 7 , wherein
said anchor element is disposed on each of said proximal end and said distal end of said body portion, wherein said anchor element is configured to secure the apparatus within the blood vessel after the insertion of the apparatus.
9. The method of claim 7 , wherein said anchor element is constructed of a self-expanding material.
10. The method of claim 7 , wherein the apparatus further comprises at least one marker element disposed on said anchor element.
11. The method of claim 7 , wherein the method further comprises repositioning the apparatus prior to withdrawing the microcatheter.
12. The method of claim 7 , wherein the nerve is a cranial nerve.
13. The method of claim 12 , wherein the cranial nerve is a trigeminal nerve.
14. The method of claim 7 , wherein the method further comprises mechanically restructuring the blood vessel using the apparatus to reduce blood vessel pulsation.
15. The method of claim 7 , wherein the method further comprises measuring a length of curvature of the blood vessel and a diameter of the blood vessel to select an apparatus having sufficient length and rigidity to change the geometry of the blood vessel.
16. The apparatus of claim 1 , wherein the body portion is configured to have a rigidity of about 0.5 N/mm bending moment.
17. The apparatus of claim 1 , wherein the body portion is configured to have a length of approximately the length of the curvature in the blood vessel.
18. The apparatus of claim 1 , wherein the body portion is configured to have a length of about 5 mm to about 20 mm.
19. The apparatus of claim 1 , wherein the body portion is configured to have a diameter based on the diameter of the blood vessel, the body portion diameter being about 1.0 mm to about 4.0 mm.
20. An apparatus configured to change a geometry of a blood vessel in contact with a nerve, the apparatus comprising:
a body portion having a proximal end and a distal end; and
one or more marker elements disposed on said body portion;
said body portion comprising at least two wires wrapped about one another to form a braided wire, the body portion being sized and shaped to change the geometry of the blood vessel upon insertion of the apparatus into the blood vessel to no longer contact the nerve, and being configured to have a rigidity of about 0.5 N/mm bending moment and a length, the rigidity and length selected based on a length of a curvature in the blood vessel and a diameter of the blood vessel, the rigidity controlled by one or more of the number of wires of the braided wire, a thickness of the wires, and a material of the wires, the rigidity being sufficient to retain the changed geometry of the blood vessel with the apparatus positioned therein and reduce or eliminate blood vessel pulsation.
21. A method for treating vascular nerve compression comprising:
using a guidewire to position a microcatheter within a blood vessel at a site of the vascular nerve compression;
withdrawing the guidewire from the microcatheter and inserting an apparatus into the microcatheter;
positioning the apparatus at the site of the vascular nerve compression;
repositioning the apparatus prior to withdrawing the microcatheter;
withdrawing the microcatheter from the site of vascular nerve compression to deploy the apparatus; and
repositioning the blood vessel using the apparatus to no longer contact a nerve and reduce the vascular nerve compression;
wherein the apparatus comprises:
a body portion having a proximal end and a distal end; and
one or more marker elements disposed on said body portion;
said body portion comprising at least two wires wrapped about one another to form a braided wire, the body portion being sized and shaped to change the geometry of the blood vessel upon insertion of the apparatus into the blood vessel to no longer contact the nerve, and being configured to have a rigidity and a length, the rigidity and length selected based on a length of a curvature in the blood vessel and a diameter of the blood vessel, the rigidity controlled by one or more of the number of wires of the braided wire, a thickness of the wires, and a material of the wires, the rigidity being sufficient to retain the changed geometry of the blood vessel with the apparatus positioned therein and reduce or eliminate blood vessel pulsation.