SLEEP DISORDER COMPOSITIONS AND TREATMENTS THEREOF
The invention relates to a pharmaceutical composition comprising a Cannabis extract and optionally one or more pharmaceutically acceptable carriers, diluents, adjuvants, excipients or any combination thereof, the Cannabis extract comprising a cannabinoid fraction comprising Δ9-Tetrahydrocannabinol (THC), Cannabidiol (CBD), and Cannabinol (CBN) and a terpene fraction in an amount of at least 3% by weight of the extract. The invention also relates to methods of treating sleep disorders using this pharmaceutical composition.
1 . A pharmaceutical composition comprising a Cannabis extract and optionally one or more pharmaceutically acceptable carriers, diluents, adjuvants, excipients or any combination thereof, the Cannabis extract comprising a cannabinoid fraction comprising Δ 9 -Tetrahydrocannabinol (THC), Cannabidiol (CBD), and Cannabinol (CBN) and a terpene fraction in an amount of at least 3% by weight of the extract.
2 . The pharmaceutical composition of claim 1 , comprising THC in an amount from 5% to 90% by weight of the extract.
3 . The pharmaceutical composition of claim 1 , comprising CBD in an amount from 1% to 20% by weight of the extract.
4 . The pharmaceutical composition of claim 1 , comprising CBN in an amount from 1% to 20% by weight of the extract.
5 . The pharmaceutical composition of claim 1 , wherein the terpene fraction comprises one or more of linalool, myrcene, and nerolidol.
6 . The pharmaceutical composition of claim 1 , wherein the terpene fraction comprises beta-myrcene in an amount from 1% to 50% by weight of the terpene fraction.
7 . The pharmaceutical composition of claim 1 , wherein the THC is a main cannabinoid.
8 . The pharmaceutical composition of claim 1 , wherein the ratio of THC:CBN is from 5:1 to 20:1.
9 . The pharmaceutical composition of claim 1 , wherein the ratio of THC:CBD is from 10:1 to 50:1.
10 . The pharmaceutical composition of claim 1 , wherein the Cannabis extract is a Cannabis oil.
11 . The pharmaceutical composition of claim 1 , the Cannabis extract comprises the terpene fraction in an amount of less than 50% by weight of the extract.
12 . The pharmaceutical composition of claim 1 , wherein the ratio of the cannabinoid fraction:terpene fraction is about 8:1 to about 33:1.
13 . (canceled)
14 . A medicament comprising an effective amount of the pharmaceutical composition of claim 1 .
15 . A method for treating a sleep disorder, comprising administering to a patient in need thereof an effective amount of the pharmaceutical composition of claim 1 .
16 . (canceled)