Cannabinoid pouch
View Patent ↗A pouch designed for administration of an active ingredient in the oral cavity is disclosed, the pouch containing a matrix composition having a combination of an amount of one or more cannabinoids and a water-insoluble composition. Also, pouches for use as a medicament, for use in alleviation of pain, and for use in mitigation of appetite deficiency are disclosed. Further, a method of alleviation of pain and a method of mitigation of appetite deficiency using the pouch are disclosed.
1. A pouch designed for administration of an active ingredient in the oral cavity, the pouch containing a matrix composition comprising:
powdered granules comprising a combination of
an amount of one or more cannabinoids; and
a water-insoluble composition comprising microcrystalline cellulose (MCC), wherein the matrix composition further comprises a water-soluble composition comprising one or more sugar alcohols, and wherein the pouch comprises a water-permeable membrane.
2. The pouch according to claim 1 , wherein the matrix composition comprises said water-insoluble composition in an amount of between 1 and 80 percent by weight of said matrix composition.
3. The pouch according to claim 1 , wherein the water-insoluble composition further comprises an ion-exchange resin.
4. The pouch according to claim 3 , wherein the ion-exchange resin is present in an amount of 5 to 60 percent of said matrix composition.
5. The pouch according to claim 1 , wherein the matrix composition further comprises a release controlling composition.
6. The pouch according to claim 5 , wherein said release controlling composition is hydrophobic.
7. The pouch according to claim 5 wherein said release controlling composition comprises one or more metallic stearates.
8. The pouch according to claim 5 , wherein the matrix composition comprises said release controlling composition in an amount of between 1 and 20 percent by weight of said matrix composition.
9. The pouch according to claim 1 , wherein the one or more cannabinoids is physically or chemically bound to at least a part of the matrix composition acting as a carrier.
10. The pouch according to claim 1 , wherein the one or more cannabinoids comprises cannabidiol.
11. The pouch according to claim 1 , wherein the one or more cannabinoids comprises tetrahydrocannabinol.
12. The pouch according to claim 1 , wherein the pouch further comprises a humectant.
13. A pouch designed for administration of an active ingredient in the oral cavity, the pouch containing a matrix composition comprising:
a powder composition comprising
an amount of one or more cannabinoids;
a water-soluble composition comprising one or more sugar alcohols; and
a water-insoluble composition comprising microcrystalline cellulose (MCC), wherein the pouch comprises a water-permeable membrane.
14. A pouch designed for administration of an active ingredient in the oral cavity, the pouch containing a powdered matrix composition comprising:
an amount of one or more cannabinoids;
a water-soluble composition comprising one or more sugar alcohols; and
a water-insoluble composition comprising microcrystalline cellulose (MCC), wherein the one or more cannabinoids is physically or chemically bound to at least a part of the powdered matrix composition acting as a carrier, and wherein the pouch comprises a water-permeable membrane.
15. The pouch according to claim 13 , wherein the water-permeable membrane is a woven fabric.
16. The pouch according to claim 13 , wherein the water-permeable membrane is a non-woven fabric.
17. The pouch according to claim 13 , wherein the matrix composition comprises said one or more cannabinoids in an amount of 0.25 to 500 milligrams.
18. The pouch according to claim 13 , wherein the one or more cannabinoids is physically or chemically bound to at least a part of the matrix composition acting as a carrier.
19. The pouch according to claim 13 , wherein the matrix composition comprises said water-insoluble composition in an amount of between 1 and 80 percent by weight of said matrix composition.
20. The pouch according to claim 14 , wherein the one or more cannabinoids comprises cannabidiol and/or tetrahydrocannabinol.
21. The pouch according to claim 14 , wherein the pouch further comprises a humectant.
22. The pouch according to claim 14 , wherein the powdered matrix composition has an average particle size between 1 and 1200 micrometers.