IP Library Granted Patent US 11,547,777
Granted Patent B2
US 11,547,777 · App. 16/626,811 · Granted Jan 10, 2023

Thermally robust, electromagnetic interference compatible, devices for non-invasive and invasive surgery

Inventors: Sanjeet Hegde (San Diego, CA); Kanishka Ratnayaka (San Diego, CA); John Moore (San Diego, CA); Sunghoon Park (Seoul, KR); Prabhakar Bandaru (San Diego, CA)
Assignee: The Regents of the University of California
A61L27/306A61L29/103A61L29/106A61L31/088B82Y30/00A61L2400/12A61L2420/06
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Quick Facts
Patent No.
US 11,547,777
App. No.
16/626,811
Granted
Jan 10, 2023
Kind
B2
Abstract

Techniques to fabricate and use a nanocomposite coating that includes one or more nanotubes such as carbon nanotubes are disclosed. In some examples, a guidewire may include the nanocomposite material. The guidewire is immune to electromagnetic interference, is thermally robust, and is capable of accommodating inactive markers and active electronics.

Claims (22)

1. A device comprising:

a base layer that is part of a medical instrument; and

one or more coatings of a nanomaterial structure over the base layer, the nanomaterial structure including a polymer matrix and a plurality of nanomaterial fillers dispersed in the polymer matrix such that the plurality of nanomaterial fillers are aligned in a plane of the polymer matrix,

wherein the polymer matrix includes reactive ethylene terpolymer (RET) matrix including an epoxide functional group and nanomaterial fillers includes carboxyl group functionalized single-walled carbon nanotubes or multiwalled carbon nanotubes to form ester bond linkages between the carboxyl group functionalized nanotubes and the epoxide functional group.

2. The device of claim 1 , wherein the plurality of nanomaterial fillers comprises at least one of nanotubes, nanowires, or nanofibers.

3. The device of claim 1 , wherein the medical instrument includes a device suitable for non-invasive surgery.

4. The device of claims 1 , wherein base layer is at least a portion of a catheter, an access needle, a transseptal needle, an aspiration needle, an injection needle, a biopsy needle, a chemoablation needle, a medical sheath, a medical dilator, a valve, a device delivery system, a stent, an endograft, a trocar, an access port, an insufflator, a laser device, a shunt, a graft, a snare catheter, a balloon catheter, or an implantable device.

5. The device of claim 1 , wherein the plurality of nanomaterial fillers includes oblong shape filler composite materials.

6. The device of claim 1 , wherein the plurality of nanomaterial fillers includes nanomaterial fillers with various length to mean diameter aspect ratios to tune electrical conductivity and thermal conductivity of the nanomaterial structure.

7. The device of claim 1 , wherein the plurality of nanomaterial fillers comprises a carbon-based nanomaterial.

8. The device of claim 7 , wherein the carbon-based nanomaterial includes carbon black spheres.

9. The device of claim 1 , wherein the plurality of nanomaterial fillers is arranged in the polymer matrix to change an electrical conductivity of the nanomaterial structure.

10. The device of claim 1 , wherein the plurality of nanomaterial fillers is arranged in the polymer matrix to change a thermal conductivity of the nanomaterial structure.

11. The device of claim 1 , wherein the device is embedded with non-active fiducial markers.

12. The device of claim 1 , wherein the device is embedded with active electronic elements.

13. The device of claim 1 , further comprising at least one of a non-active marker or an active marker.

14. The device of claim 1 , further comprising a plurality of markers periodically placed on the device.

15. A method of manufacturing a medical device, comprising:

synthesizing a composite that includes a polymer matrix and a plurality of nanomaterial fillers dispersed in the polymer matrix; and

forming a layer of the composite along a surface of a base layer of the medical device such that the plurality of nanomaterial fillers are aligned in a plane of the polymer matrix,

wherein the polymer matrix includes reactive ethylene terpolymer (RET) matrix including an epoxide functional group and nanomaterial fillers includes carboxyl group functionalized single-walled carbon nanotubes or multiwalled carbon nanotubes to form ester bond linkages between the carboxyl group functionalized nanotubes and the epoxide functional group.

16. The method of claim 15 , wherein the forming the layer of the composite includes spray coating the composite along the surface of the base layer.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 7, 2020
From: BANDARU, PRABHAKAR R.; HEGDE, SANJEET; PARK, SUNGHOON; RATNAYAKA, KANISHKA; MOORE, JOHN
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 053140/0919 →
CONFIRMATORY LICENSE Recorded Jan 23, 2020
From: UNIVERSITY OF CALIFORNIA, SAN DIEGO
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 051684/0918 →
Continuity (2)
Provisional Application 62525034 · Jun 26, 2017
Related Publication 20200114042A1 · Apr 16, 2020