Control of resistant pests

1. A method of controlling pesticide resistant pests comprising exposing the pesticide resistant pests to a compound of formula (I)

wherein:

R 1 is selected from the group consisting of —C(═O)R 7 , —OR 8 , —SR 8 , —C 1-10 hydroxyalkyl, —NR 9 R 10 , —C(═N—R 9 )R 7 , —C(═N—OH)R 7 , —NO, —NO 2 , —N(OR 8 )R 7 and —OSO 3 R 8 ;

R 2 is hydrogen;

R 3 , R 4 , R 5 and R 6 are each independently selected from the group consisting of hydrogen, —C 1-10 alkyl, —C 3-6 cycloalkyl, —C 2-10 alkenyl, —C 1-10 haloalkyl, —C 1-10 dihaloalkyl, —C 1-10 trihaloalkyl, —OR 8 , —SR 8 , —NR 9 R 10 , —C(═N—R 9 )R 7 , —NO, —NO 2 , —NR 9 OR 8 , —OSO 3 R 8 , —C 1-10 alkylaryl and —C(═O)R 7 ;

R 7 is selected from the group consisting of hydrogen, —C 1-10 alkyl, —C 2-10 alkylaryl, C 3-6 cycloalkyl, —C 2-10 alkenyl, —C 1-10 alkylheteroaryl, —C 1-10 haloalkyl, —C 1-10 dihaloalkyl, —C 1-10 trihaloalkyl, —C 1-10 haloalkoxy, —C 1-10 hydroxyalkyl, —C 1-10 thioalkyl, —C 1-10 nitroalkyl, —C 1-3 alkylOC 1-3 alkyl, —C 1-3 alkylOC 1-3 haloalkyl, —C 1-3 alkylOC 1-3 dihaloalkyl, —C 1-3 alkylOC 1-3 trihaloalkyl, —OR 8 , —SR 8 and —NR 9 R 10 ;

R 8 is selected from the group consisting of hydrogen, —C 1-10 alkyl, —C 2-10 alkylaryl, —C 3-6 cycloalkyl, —C 2-10 alkenyl, —C 1-10 alkylheteroaryl, —C 1-10 haloalkyl, —C 1-10 dihaloalkyl, —C 1-10 trihaloalkyl, —C 1-10 haloalkoxy, —C 1-10 hydroxyalkyl, —C 1-10 thioalkyl and —C 1-10 nitroalkyl;

R 9 and R 10 are independently selected from the group consisting of hydrogen, —C 1-10 alkyl, —C 2-10 alkylaryl, —C 3-6 cycloalkyl, —C 2-10 alkenyl, —C 1-10 alkylheteroaryl, —C 1-10 haloalkyl, —C 1-10 dihaloalkyl, —C 1-10 trihaloalkyl; or a tautomer thereof.

2. The method according to claim 1 , wherein the compound of formula (I) is a compound of formula (II):

wherein

R 11 is selected from —CR 12 R 13 R 14 or —NR 15 R 16 ;

one of R 12 and R 13 is hydrogen and the other is hydroxyl or —OCR 17 R 18 R 19 or R 12 and R 13 together form an oxo group (═O) or a ═N—OH group;

R 14 is —CH(CH 3 )CR 20 R 21 R 22 , —CH 2 CH(CH 3 )CR 20 R 21 R 22 or —CH(CH 3 )CH 2 CR 20 R 21 R 22 ;

R 15 and R 16 are independently selected from hydrogen and C 1-10 alkyl;

R 17 , R 18 and R 19 are independently selected from hydrogen or halo; and

R 20 , R 21 and R 22 are independently selected from hydrogen, hydroxyl, halo, NO 2 and —OCR 17 R 18 R 19 ; or a tautomer thereof.

3. The method according to claim 1 , wherein the compound of formula (I) is a compound of formula (III):

wherein one of R 23 and R 24 is hydrogen and the other is hydroxyl or —OCR 27 R 28 R 29 or R 23 and R 24 together form an oxo group (═O);

R 25 is —CR 30 R 31 R 32 , —CH 2 CR 30 R 31 R 32 or —CH(CH 3 )CR 30 R 31 R 32 ;

R 26 is H or —CH 3 ; wherein where R 26 is H, R 25 is —CH(CH 3 )CR 30 R 31 R 32 ;

R 27 , R 28 and R 29 are independently selected from hydrogen or halo; and

R 30 , R 31 and R 32 are independently selected from hydrogen, hydroxyl, halo, NO 2 and —OCR 27 R 28 R 29 ; or a tautomer thereof.

4. The method according to claim 1 , wherein the compound of formula (I) is selected from the group consisting of:

or a tautomer thereof.

5. The method according to claim 1 , wherein the compound of formula (I) is selected from the group consisting of flavesone, leptospermone and isoleptospermone.

6. The method according to claim 5 , wherein, the compound of formula (I) is flavesone.

7. The method according to claim 1 , wherein the pesticide resistant pest is exposed to the compound of formula (I) in an amount in the range of about 200 ppm to about 800 ppm or about 300 ppm to about 600 ppm or about 800 ppm to about 2,500 ppm or about 900 ppm to about 2000 ppm.

8. The method according to claim 1 , wherein the pesticide resistant pests are insects resistant to one or more insecticides or arachnids resistant to one or more arachnicides.

9. The method according to claim 8 , wherein the insects are selected from the order of Lepidoptera, Diptera, Heteroptera and Isoptera.

10. The method according to claim 8 , wherein the insects are selected from the order of Diptera.

11. The method according to claim 8 , wherein the insects are adults.

12. The method according to claim 8 , wherein the arachnids are selected from the group consisting of spiders and daddy long legs.

13. The method according to claim 1 , wherein a pesticide resistant pest is exposed to a compound of formula (I) in combination with a second pesticide, wherein the second pesticide has a different mode of action from the compound of formula (I).

14. The method according to claim 13 , wherein the second pesticide is selected from at least one of a sodium channel modulator, an acetylcholinesterase (AChE) inhibitor, a GABA-gated chloride channel antagonist, a nicotinergic acetylcholine receptor agonist, an allosteric acetylcholine receptor modulator, a chloride channel actuator, a juvenile hormone mimic, a homopteran feeding blocker, a mitochondrial ATP synthase inhibitor, an uncoupler of oxidative phosphorylation, a nicotinic acetylcholine receptor channel blocker, an inhibitor of chitin biosynthesis, a moulting disruptor, an ecdysone receptor agonist or disruptor, an octapamine receptor agonist, a mitochondrial complex I electron transport inhibitor, an acetyl CoA carboxylase inhibitor, a voltage-dependent sodium channel blocker, a mitochondrial complex IV electron inhibitor, a mitochondrial complex IV electron transport inhibitor or a ryanodine receptor modulator.

15. The method according to claim 1 , wherein the pesticide resistant pests are infesting a household or industrial environment, said method comprising applying to the household or industrial environment a compound of formula (I).

16. The method according to claim 15 , wherein the household environment is an indoor environment and includes carpets, curtains, cupboards, bed and bedding, animal beds and blankets, or the air of the indoor environment.

17. The method according to claim 15 , wherein the household environment is an outdoor environment and includes a domestic garden or an animal shelter.

18. The method according to claim 15 , wherein the industrial environment is selected from the group consisting of a warehouse, manufacturing facility, shop and storage facility.