Cryoablation devices and related methods

1. A method of performing a gallbladder ablation, the method comprising:

positioning a cryoablation device within a gallbladder, wherein the cryoablation device comprises:

(a) an elongate body;

(b) an expandable balloon operably coupled to the elongate body;

(c) a cryogen conduit associated with the elongate body, wherein the cryogen conduit is operably coupled to the expandable balloon; and

(d) at least one first suction opening defined in the elongate body;

filling the expandable balloon with cryogen via the cryogen conduit; and

causing the gallbladder to contract and thereby contact the expandable balloon by applying suction via a lumen within the elongate body and the at least one first suction opening.

2. The method of claim 1 , wherein the elongate body is a cryoprobe body or a catheter body.

3. The method of claim 1 , wherein the positioning the cryoablation device within the gallbladder further comprises:

advancing a guidewire into the gallbladder; and

advancing the cryoablation device into the gallbladder over the guidewire.

4. The method of claim 1 , further comprising:

removing the cryogen from the expandable balloon, thereby causing the expandable balloon to contract; and

retracting the cryoablation device from the gallbladder.

5. The method of claim 1 , wherein the positioning the cryoablation device within the gallbladder further comprises positioning the cryoablation device within a sheath.

6. The method of claim 1 , further comprising positioning the cryoablation device within a sheath.

7. The method of claim 1 , wherein the applying the suction can occur before, during, or after the filling the expandable balloon with cryogen.

8. A method of performing a gallbladder ablation, the method comprising:

positioning a cryoablation device within a gallbladder, wherein the cryoablation device comprises:

(a) a cryogen probe comprising an elongate probe body;

(b) an elongate slidable body slidably positioned over the elongate probe body, the elongate slidable body comprising:

(i) a probe lumen defined within the elongate slidable body, wherein the elongate slidable body is slidably positioned over the elongate probe body such that the elongate probe body is disposed within the probe lumen; and

(ii) a suction lumen defined within the elongate slidable body;

(c) at least one suction opening defined in an outer wall of the elongate slidable body, wherein the at least one suction opening is in fluid communication with the suction lumen; and

(d) a fluid tube coupled with the elongate slidable body, the fluid tube comprising a fluid tube lumen in fluid communication with the suction lumen of the elongate slidable body;

filling the cryogen probe with cryogen via a cryogen conduit; and

causing the gallbladder to contract and thereby contact the elongate slidable body by applying suction via the fluid tube, the suction lumen, and the at least one suction opening.

9. The method of claim 8 , wherein the positioning the cryoablation device within the gallbladder further comprises:

advancing a guidewire into the gallbladder; and

advancing the elongate probe body and the elongate slidable body into the gallbladder over the guidewire, wherein the elongate probe body is advanced over the guidewire before the elongate slidable body or the elongate slidable body is advanced over the guidewire before the elongate probe body or the elongate probe body and the elongate slidable body are advanced over the guidewire together.

10. The method of claim 8 , wherein the positioning the cryoablation device within the gallbladder further comprises:

advancing the elongate slidable body and a dilator into the gallbladder;

removing the dilator; and

advancing the elongate probe body into the elongate slidable body in the gallbladder.

11. The method of claim 8 , wherein the applying the suction can occur before, during, or after the filling the cryogen probe with cryogen.

12. A method of performing a gallbladder ablation, the method comprising:

positioning a cryoablation device within a gallbladder, wherein the cryoablation device comprises:

(a) an elongate body; and

(b) a cryogenic ablation component associated with the elongate body;

delivering a cryogen to the cryogenic ablation component; and

creating a pressure differential between an interior of the gallbladder and an exterior of the gallbladder such that a wall of the gallbladder contracts around the cryoablation device.

13. The method of claim 12 , wherein the creating the pressure differential between the interior of the gallbladder and the exterior of the gallbladder minimizes a cryoablation zone around the cryoablation device and the gallbladder.

14. The method of claim 12 , wherein the cryogenic ablation component comprises an expandable balloon or a distal portion of the elongate body.

15. The method of claim 12 , wherein the creating the pressure differential comprises applying suction via a suction component associated with the elongate body.

16. The method of claim 12 , further comprising positioning the cryoablation device within a sheath.

17. The method of claim 12 , further comprising retaining at least a portion of the cryoablation device within the gallbladder by deploying a retention structure associated with the elongate body.

18. The method of claim 12 , wherein the elongate body is a cryoprobe body or a catheter body.

19. A method of performing a gallbladder ablation, the method comprising:

positioning a cryoablation device within a gallbladder, wherein the cryoablation device comprises:

(a) an elongate body;

(b) a cryogenic ablation component associated with the elongate body; and

(c) a suction component associated with the elongate body;

delivering a cryogen to the cryogenic ablation component; and

applying suction within the gallbladder via the suction component such that the gallbladder contracts around the cryoablation device.

20. The method of claim 19 , wherein the suction component comprises at least one suction opening defined in the elongate body or in an elongate slidable body slidably positioned over the elongate body.