Encapsulation of gastric residence systems

1. A method for encapsulating a compactable gastric residence system having a plurality of elongate members, each elongate member having a proximal end attached to a linking member and each elongate member having a distal end not attached to the linking member, where the distal end is located at a larger radial distance from the linking member than the proximal end, comprising:

receiving the compactable gastric residence system in an uncompacted form;

orienting the compactable gastric residence system into a compacting position on a surface of a tapered tube having an aperture;

compacting the compactable gastric residence system into a compacted form by reducing a distance between the distal ends of each elongate member, by applying a force to the linking member and causing the linking member and plurality of elongate members to pass through the aperture, causing the distal end of each elongate member to come together; and

inserting the compactable gastric residence system in the compacted form into an opening of a container;

wherein the aperture has a radius smaller than a radius of an opening of the container.

2. A method for encapsulating a compactable gastric residence system as in claim 1 , wherein the compactable gastric residence system has an elastic characteristic that causes the compactable gastric residence system to configure in the uncompacted form when no external force is applied to the compactable gastric residence system.

3. A method for encapsulating a compactable gastric residence system as in claim 1 , wherein orienting the compactable gastric residence system includes at least one of securing the compactible gastric residence system with a pneumatic clamp and securing a portion of the linking member with a vacuum cup, wherein a shape of at least a portion of the linking member is configured to mate with the vacuum cup.

4. A method for encapsulating a compactable gastric residence system as in claim 1 , wherein the aperture is located at an end of the tapered tube, wherein a force applied by the tapered tube causes the plurality of elongate members of the compactable gastric residence system to compress into the compacted form.

5. A method for encapsulating a compactable gastric residence system as in claim 1 , wherein applying the force to the linking member causes the compactable gastric residence system to partially enter the container and the method further comprises applying a second force to the distal ends of the elongate members of the compactable gastric residence system until the entire compactable gastric residence system passes through the aperture.

6. A method for encapsulating a compactable gastric residence system as in claim 1 , wherein after passing through the aperture, a partial portion of the compactable gastric residence system extends beyond the opening of the container.

7. A method for encapsulating a compactable gastric residence system as in claim 1 , further comprising:

securing a retaining fixture to the compactable gastric residence system configured to resist expansion of the compactable gastric residence system from the compacted form to the uncompacted form,

wherein the retaining fixture couples to the distal ends of each of the elongate members of the compactible gastric residence system.

8. A method for encapsulating a compactable gastric residence system as in claim 1 , the method further comprising applying a cap to the container to create a sealed enclosure containing the compactable gastric residence system.

9. A method for encapsulating a compactable gastric residence system as in claim 7 , wherein an outer radius of the retaining fixture is smaller than an inner radius of the container such that a gap is formed between the retaining fixture and the container, wherein the gap between the outer radius of the retaining fixture and the inner radius of the container has a minimum size of at least about 0.01 millimeters, at least about 0.05 millimeters, at least about 0.1 millimeters, or at least about 0.2 millimeters, and a maximum size of about 0.15 millimeters, about 0.2 millimeters, or about 0.25 millimeters.

10. A method for encapsulating a compactable gastric residence system as in claim 7 , wherein the retaining fixture is configured to maintain a spacing between the elongate members of the compactable gastric residence system in the compressed form.

11. A method for encapsulating a compactable gastric residence system as in claim 10 , wherein the spacing between the elongate members of the compactable gastric residence system in the compressed form has a minimum size of at least about 0.01 millimeters, at least about 0.05 millimeters, at least about 0.075 millimeters, or at least about 0.1 millimeters, and a maximum size of about 0.15 millimeters, about 0.125 millimeters, or about 0.1 millimeters.

12. A method for encapsulating a compactable gastric residence system as in claim 1 , wherein the linking member is an elastomer, and the container is a capsule or a half-capsule.

13. A method for encapsulating a compactable gastric residence system as in claim 1 , wherein a force for maintaining the compactable gastric residence system in the compressed form is at least about 0.1 newtons, at least about 0.2 newtons, at least about 0.4 newtons, at least about 0.6 newtons, or at least about 1.5 newtons, and at most about 2 newtons, at most about 4 newtons, or at most about 5 newtons.