IP Library Granted Patent US 11,819,235
Granted Patent B2
US 11,819,235 · App. 16/665,631 · Granted Nov 21, 2023

Method and system for harvesting biological tissue

Inventors: Marvin A. Guiles (Stow, MA); Denis Labombard (Georgetown, MA); Charles Sidoti (Plymouth, MA); Philip S. Levin (Storrs, CT); Thomas Swyst (Arlington, MA); Sameer Sabir (Arlington, MA)
Assignee: Medline Industries, LP
A61B17/32053A61B17/3205A61B17/3421A61B5/15142A61B5/150396A61B5/150503
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Quick Facts
Patent No.
US 11,819,235
App. No.
16/665,631
Granted
Nov 21, 2023
Kind
B2
Abstract

In one aspect, the dual bevel needle can include a hollow tube having a proximal end, a distal end, a first lateral side, and a second lateral side opposite the first lateral side; a first needle point at the distal end of the hollow tube; a second point at the distal end of the hollow tube; a first bevel on each of the first lateral side and the second lateral side, the first bevel comprising a first bevel angle relative to a longitudinal axis of the tube; and a second bevel on each of the first lateral side and the second lateral side, the second bevel having a second bevel angle relative to the longitudinal axis of the tube, wherein the first and second bevels each form a portion of an ellipse, the ellipse having an inner cutting edge and terminating in the first and second needle points at the distal end of the tube, the second bevel angle being shallower than the first bevel angle, the second bevel being located adjacent the proximal end of the first bevel, and the inner cutting edge converging to a narrow heel.

Claims (69)

1. A method for harvesting biological tissue, the method comprising:

providing a device having a plurality of rows of hollow tubes, each hollow tube comprising at least one point at a distal end of the hollow tube, the plurality of rows forming a two dimensional array of hollow tubes, and a plurality of pins, each of the pins provided within a central lumen of each of the hollow tubes;

positioning the two dimensional array of hollow tubes proximal to an upper surface of a biological tissue;

securing the device to the biological tissue, wherein securing comprises:

attaching the device to the biological tissue with a strap;

attaching the device to the biological tissue with an adhesive; or

attaching the device to the biological tissue with a clamp;

advancing the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from surrounding tissue such that the distal end of the pins are positioned proximal to the upper surface of the biological tissue; and

raising the two dimensional array of hollow tubes and the pins simultaneously such that the biological tissue remains in each of the hollow tubes.

2. The method of claim 1 , wherein securing comprises locking the device into a base on the strap.

3. The method of claim 1 , wherein securing comprises positioning a tissue stabilization housing adjacent to the biological tissue.

4. The method of claim 1 , further comprising measuring an amount of force applied by the device to the biological tissue.

5. The method of claim 4 , further comprising providing a notification when an optimal amount of force has been applied.

6. The method of claim 1 , further comprising measuring an angle at which the device is applied to the biological tissue.

7. The method of claim 6 , further comprising providing a notification of the angle.

8. The method of claim 1 , wherein advancing the two dimensional array of hollow tubes into the biological tissue to sever portions the biological tissue comprises skin tissue and adipose tissue.

9. The method of claim 1 , further comprising:

opening a disposable package to allow the device to access a disposable array that includes the plurality of rows of hollow tubes; and

locking the device into the disposable array.

10. The method of claim 1 , wherein each hollow tube comprises two points at a distal end of each hollow tube; and

wherein each hollow tube includes four bevels.

11. A device for harvesting biological tissue, the device comprising:

a plurality of rows of hollow tubes, each hollow tube comprising at least one point at a distal end of the hollow tube, the plurality of rows forming a two dimensional array of hollow tubes, and a plurality of pins, each of the pins provided within a central lumen of each of the hollow tubes;

an attachment device configured to secure the device to a donor site, the attachment device comprising a strap, an adhesive, or a clamp; and

a force sensor configured to detect a force with which the device is applied to the donor site.

12. The device of claim 11 , wherein the strap comprises a base for receiving the device into the strap.

13. The device of claim 11 , wherein the strap comprises a plurality of ports for receiving the device into the strap at various locations along the strap.

14. The device of claim 11 , wherein the donor site comprises skin tissue and adipose tissue.

15. The device of claim 11 , further comprising a second sensor configured to measure an angle at which the device is applied to the donor site; and

wherein the second sensor is configured to generate an alert when the device is applied at an unacceptable angle.

16. The device of claim 11 , further comprising:

a second sensor configured to measure an angle at which the device is applied to the donor site;

wherein the device is configured to notify the user when the applied force is at an optimal force or the applied force is below an acceptable level; and

wherein the device is configured to notify the user when the device is applied at an unacceptable angle.

17. A method for harvesting biological tissue, the method comprising:

providing a device having a plurality of rows of hollow tubes, each hollow tube comprising at least one point at a distal end of the hollow tube, the plurality of rows forming a two dimensional array of hollow tubes;

positioning the two dimensional array of hollow tubes proximal to an upper surface of a biological tissue;

vibrating at least one hollow tube by striking the at least one hollow tube with a strike plate;

while vibrating the at least one hollow tube, advancing the hollow tube into the biological tissue to sever a portion of the biological tissue from surrounding tissue; and

raising the hollow tube such that the biological tissue remains in the hollow tube.

18. The method of claim 17 , wherein vibrating the at least one hollow tube comprises vibrating the at least one hollow tube along an axis perpendicular to an axis of the at least one hollow tube.

19. The method of claim 18 , further comprising moving each hollow tube, independently of the strike plate.

20. The method of claim 18 , wherein vibrating the at least one hollow tube comprises vibrating at a resonant frequency of the strike plate.

21. The method of claim 18 , wherein vibrating the at least one hollow tube comprises vibrating at a non-resonant frequency of the strike plate.

22. The method of claim 18 , wherein the strike plate strikes the hollow tube in response to an actuator.

23. The method of claim 17 , wherein advancing the hollow tube into the biological tissue severs a portion of skin tissue and adipose tissue.

24. The method of claim 17 , further comprising causing an actuator to move a strike plate to vibrate the at least one hollow tube; and

wherein the actuator is at least one of an electromechanical actuator, a pneumatic actuator, a fluidic actuator, or a magnetostrictive actuator.

25. The method of claim 24 , wherein the strike plate includes a plurality of contact apertures, each of the plurality of hollow tubes being positioned within a respective contact aperture; and

wherein each contact aperture is wider than the respective hollow tube positioned therein.

26. The method of claim 17 , further comprising causing a plurality of actuators to move a strike plate to vibrate the at least one hollow tube.

27. A device for harvesting biological tissue, the device comprising:

a plurality of rows of hollow tubes, each hollow tube comprising at least one point at a distal end of the hollow tube, the plurality of rows forming a two dimensional array of hollow tubes;

a strike plate surrounding each hollow tube; and

an actuator coupled to the strike plate, wherein the actuator causes the strike plate to strike and vibrate the hollow tubes; and

wherein at least one of:

the actuator is energetically coupled to the strike plate;

a transducer energetically couples the actuator to the strike plate;

the actuator comprises a solenoid.

28. The device of claim 27 , wherein each of the hollow tubes comprises two points at the distal end of the hollow tube.

29. The device of claim 27 , wherein the actuator is physically coupled to the strike plate.

30. The device of claim 27 , wherein each hollow tube is configured to move independently of the strike plate.

31. The device of claim 27 , wherein the hollow tube is vibrated at a resonant frequency of the strike plate.

32. The device of claim 27 , wherein the hollow tube is vibrated at a non-resonant frequency of the strike plate.

33. The device of claim 27 , wherein the strike plate comprises a metal.

34. The device of claim 27 , wherein the biological tissue comprises skin tissue and adipose tissue.

35. The device of claim 27 , wherein the strike plate includes a plurality of contact apertures, each of the plurality of hollow tubes being positioned within a respective contact aperture.

36. The device of claim 27 , wherein each hollow tube includes two points at a distal end of each hollow tube; and

wherein each hollow tube includes four bevels.

Assignments (7)
PATENT SECURITY AGREEMENT Recorded May 28, 2026
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 075643/0462 →
PATENT SECURITY AGREEMENT Recorded Jun 20, 2025
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 071672/0100 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2023
From: SEVENOAKS BIOSYSTEMS, LLC
To: MEDLINE INDUSTRIES, INC.
Reel/Frame 063975/0099 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2023
From: GUILES, MARVIN A.; LABOMBARD, DENIS; SIDOTI, CHARLES; LEVIN, PHIL; SWYST, THOMAS; SABIR, SAMEER
To: SEVENOAKS BIOSYSTEMS, LLC
Reel/Frame 063974/0948 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 057927/0091 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: BANK OF AMERICA, N.A.
Reel/Frame 058040/0001 →
CHANGE OF NAME Recorded Oct 14, 2021
From: MEDLINE INDUSTRIES, INC.
To: MEDLINE INDUSTRIES, LP
Reel/Frame 057807/0297 →
Continuity (3)
Division 14957846 · Dec 3, 2015
Provisional Application 62151209 · Apr 22, 2015
Related Publication 20200060715A1 · Feb 27, 2020