Modulators of hemoglobin
The present disclosure relates generally to compounds and pharmaceutical compositions suitable as modulators of hemoglobin, and methods for their use in treating disorders mediated by hemoglobin.
1. A compound of formula:
or a pharmaceutically acceptable salt of each thereof.
2. A compound of formula:
or a pharmaceutically acceptable salt thereof.
3. A compound of formula:
4. A compound of formula:
or a pharmaceutically acceptable salt thereof.
5. A compound of formula:
6. A compound of formula:
or a pharmaceutically acceptable salt thereof.
7. A compound of formula:
8. A compound of formula:
or a pharmaceutically acceptable salt thereof.
9. A compound of formula:
10. A compound of formula:
or a pharmaceutically acceptable salt thereof.
11. A compound of formula:
12. A compound of formula:
or a pharmaceutically acceptable salt thereof.
13. A compound of formula:
14. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
15. A pharmaceutical composition comprising a compound of claim 3 and a pharmaceutically acceptable excipient.
16. A pharmaceutical composition comprising a compound of claim 5 and a pharmaceutically acceptable excipient.
17. A pharmaceutical composition comprising a compound of claim 7 and a pharmaceutically acceptable excipient.
18. A pharmaceutical composition comprising a compound of claim 9 and a pharmaceutically acceptable excipient.
19. A pharmaceutical composition comprising a compound of claim 11 and a pharmaceutically acceptable excipient.
20. A pharmaceutical composition comprising a compound of claim 13 and a pharmaceutically acceptable excipient.