INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS TO ADDRESS EYE DISORDERS
A method may include accessing an artery in communication with an ophthalmic artery of a subject, and advancing a microcatheter along the accessed artery so as to align a distal end of the microcatheter with an ostium of the ophthalmic artery, wherein the microcatheter includes a lumen having a guidewire positioned therein. In addition, the method includes proximally withdrawing the guidewire relative to the microcatheter so as to enable a distal portion of the microcatheter to assume a curved relaxed configuration, and cannulating the ostium with the distal portion of the microcatheter when the distal portion is in the curved relaxed configuration.
1 . A method, comprising:
acquiring an optical coherence tomography (OCT) en face image of a target anatomy of a subject;
acquiring one or more OCT cross-sectional images of the target anatomy;
identifying one or more dark areas in the acquired OCT en face image;
selecting one or more OCT cross-sectional images corresponding to the identified one or more OCT en face image dark areas;
identifying one or more dark areas in each of the selected OCT cross-sectional images;
identifying one or more layers in each of the selected one or more OCT cross-sectional images in which photoreceptors reside;
determining whether the identified one or more OCT cross-sectional image dark areas reside within the identified one or more layers; and
when the determining step determines a majority of the identified one or more OCT cross-sectional image dark areas reside within the one or more identified layers, indicating a treatment for arterial disease.
2 . The method of claim 1 , wherein the target anatomy is a fovea of the subject.
3 . The method of claim 2 , wherein, in the step of acquiring the OCT en face image of at least the fovea, an OCT en face image of the fovea, macula, and at least a majority of a retina of the subject is acquired.
4 . The method of claim 1 , wherein the OCT cross-sectional images include cross-sectional images of eye tissue and layers from a retina to a choroid of the subject.
5 . The method of claim 1 , wherein the treatment for arterial disease includes treating at least one of a blockage, a stenosis, a lesion, plaque, or other physiology of the subject.
6 . The method of claim 5 , wherein the treatment includes balloon dilation.
7 . A method, comprising:
acquiring an optical coherence tomography (OCT) en face image of a fovea of a subject;
acquiring one or more OCT cross-sectional images of the fovea, the OCT cross-sectional images including cross-sectional images of eye tissue and layers from a retina to a choroid of the subject;
identifying one or more dark areas in the acquired OCT en face image;
selecting one or more OCT cross-sectional images corresponding to the identified one or more OCT en face image dark areas;
identifying one or more dark areas in each of the selected OCT cross-sectional images;
identifying one or more layers in each of the selected one or more OCT cross-sectional images in which photoreceptors reside;
determining whether the identified one or more OCT cross-sectional image dark areas reside within the identified one or more layers; and
when the determining step determines a majority of the identified one or more OCT cross-sectional image dark areas reside within the one or more identified layers, indicating a treatment for arterial disease.
8 . The method of claim 7 , wherein, in the step of acquiring the OCT en face image of at least the fovea, an OCT en face image of the fovea, macula, and at least a majority of the retina of the subject is acquired.
9 . The method of claim 7 , wherein the treatment for arterial disease includes treating at least one of a blockage, a stenosis, a lesion, plaque, or other physiology of the subject.
10 . The method of claim 9 , wherein the treatment includes balloon dilation.
11 . The method of claim 10 , wherein the balloon dilation includes balloon dilation of an ophthalmic artery of the subject.
12 . The method of claim 7 , wherein the arterial disease includes one or more of age-related macular degeneration (AMD), glaucoma, or diabetic retinopathy.
13 . A method, comprising:
acquiring an optical coherence tomography (OCT) en face image of a fovea of a subject;
acquiring one or more OCT cross-sectional images of the fovea;
identifying one or more dark areas in the acquired OCT en face image;
selecting one or more OCT cross-sectional images corresponding to the identified one or more OCT en face image dark areas;
identifying one or more dark areas in each of the selected OCT cross-sectional images;
identifying one or more layers in each of the selected one or more OCT cross-sectional images in which photoreceptors reside;
determining whether the identified one or more OCT cross-sectional image dark areas reside within the identified one or more layers; and
when the determining step determines a majority of the identified one or more OCT cross-sectional image dark areas reside within the one or more identified layers, indicating a treatment for arterial disease, the treatment for arterial disease including treating at least one of a blockage, a stenosis, a lesion, plaque, or other physiology of the subject, and
when the determining step determines the majority of the identified one or more OCT cross-sectional image dark areas do not reside within the one or more identified layers, not indicating a treatment for arterial disease.
14 . The method of claim 13 , wherein, in the step of acquiring the OCT en face image of at least the fovea, an OCT en face image of the fovea, macula, and at least a majority of a retina of the subject is acquired.
15 . The method of claim 13 , wherein the OCT cross-sectional images include cross-sectional images of eye tissue and layers from a retina to a choroid of the subject.
16 . The method of claim 13 , wherein the treatment includes balloon dilation.
17 . The method of claim 16 , wherein the balloon dilation includes balloon dilation of an ophthalmic artery of the subject.
18 . The method of claim 13 , wherein the arterial disease includes one or more of age-related macular degeneration (AMD), glaucoma, or diabetic retinopathy.
19 . The method of claim 1 , wherein the OCT cross-sectional image is acquired by swept source OCT.
20 . The method of claim 1 , wherein the OCT cross-sectional image is acquired by spectral domain OCT.