IP Library Granted Patent US 11,098,030
Granted Patent B2
US 11,098,030 · App. 16/703,544 · Granted Aug 24, 2021

EGFR inhibitor compounds

Inventors: Kevin Duane Bunker (Escondido, CA); Peter Qinhua Huang (San Diego, CA); Sunny Abraham (San Diego, CA); Joseph Robert Pinchman (San Diego, CA); Chad Daniel Hopkins (San Diego, CA); Deborah Helen Slee (Encinitas, CA)
Assignee: Recurium IP Holdings, LLC
C07D403/04A61K31/506A61P35/00C07C13/36C07D209/04C07D403/14C07D471/04
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Quick Facts
Patent No.
US 11,098,030
App. No.
16/703,544
Granted
Aug 24, 2021
Kind
B2
Abstract

Disclosed herein are nitrogen-containing bicyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.

Claims (20)

1. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt of any of the foregoing.

2. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

3. The compound of claim 2 , wherein the compound is

4. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

5. The compound of claim 4 , wherein the compound is

6. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

7. The compound of claim 6 , wherein the compound is

8. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

9. The compound of claim 8 , wherein the compound is

10. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

11. The compound of claim 10 , wherein the compound is

12. The compound of claim 1 , wherein the compound is

or a pharmaceutically acceptable salt thereof.

13. The compound of claim 12 , wherein the compound is

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 3, 2020
From: BUNKER, KEVIN DUANE; HUANG, PETER QINHUA; ABRAHAM, SUNNY; PINCHMAN, JOSEPH ROBERT; HOPKINS, CHAD DANIEL; SLEE, DEBORAH HELEN
To: KALYRA PHARMACEUTICALS, INC.
Reel/Frame 051410/0809 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 3, 2020
From: KALYRA PHARMACEUTICALS, INC.
To: ZENO ROYALTIES & MILESTONES, LLC
Reel/Frame 051411/0006 →
CHANGE OF NAME Recorded Jan 3, 2020
From: ZENO ROYALTIES & MILESTONES, LLC
To: RECURIUM IP HOLDINGS, LLC
Reel/Frame 051483/0598 →
Continuity (3)
Division 15603789 · May 24, 2017
Provisional Application 62342141 · May 26, 2016
Related Publication 20200181120A1 · Jun 11, 2020