IP Library › Granted Patent US 11,020,066
Granted Patent B2
US 11,020,066 · App. 16/708,963 · Granted Jun 1, 2021

System and method for cabinet x-ray systems with stationary x-ray source array

Inventors: Vikram Butani (Stratford, CT); Yan Chen (Stratford, CT); Chester Lowe (Stratford, CT); Vignesh Mandalapa-Bhoopathy (Stratford, CT); Edwin Maria-Selvaraj (Stratford, CT); Roberto Velasco (Stratford, CT); Peter Yasutake (Stratford, CT)
Assignee: Kub Technologies, Inc.
A61B6/025A61B6/40A61B6/4007A61B6/42A61B6/4208A61B6/4258A61B6/44A61B6/4405A61B6/4411A61B6/4429A61B6/502A61B6/508A61B6/54A61B6/542A61B6/58A61B6/588A61B6/589G01N23/04G01N23/044G01N23/083G01N23/20025G01N2223/318G01N2223/6123G01N2223/6126
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Quick Facts
Patent No.
US 11,020,066
App. No.
16/708,963
Granted
Jun 1, 2021
Kind
B2
Abstract

The present disclosure relates to the field of a cabinet x-ray incorporating a stationary x-ray source array, and an x-ray detector, for the production of organic and non-organic images. Stationary x-ray digital cabinet tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object. In the preferred embodiment, the x-ray source or sources are statically affixed in a range from about 350° to and including about 10°.

Claims (61)

1. A cabinet x-ray system for obtaining specimen x-ray images, projection x-ray images, and reconstructed tomosynthetic x-ray images of a specimen, the cabinet x-ray system comprising:

a cabinet defining an interior chamber;

a display;

an x-ray system including:

an x-ray detector;

a plurality of fixed x-ray sources in an array, the plurality of fixed x-ray sources including fixed x-ray sources at end positions of the array, each fixed x-ray source of the fixed x-ray sources at the end positions of the array having a point source line of a beam such that an angle between point source lines of the fixed x-ray sources at the end positions of the array is from about 20° to about 50°, about 30°, or about 20°, wherein one of the plurality of fixed x-ray sources is positioned at a standard imaging angle of approximately 0° relative to the x-ray detector; and

a specimen platform; and

a controller configured to:

energize each of the plurality of fixed x-ray sources separately to emit x-rays through the specimen to the x-ray detector such that an isocenter of the emitted x-rays of each of the plurality of fixed x-ray sources is located at a surface of the x-ray detector;

control the x-ray detector to collect projection x-ray images of the specimen when each of the plurality of fixed x-ray sources are separately energized to form a collection of x-ray images, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at the standard imaging angle of approximately 0°;

create a tomosynthetic x-ray image reconstructed from the collection of projection x-ray images;

process the collection of the projection x-ray images in the controller into one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively same or different from that of the two-dimensional x-ray image; and

selectively display the two-dimensional x-ray image and the one or more reconstructed tomosynthetic x-ray images.

2. The cabinet x-ray system of claim 1 , wherein the cabinet comprises a walled enclosure surrounding the interior chamber, a door configured to cover the interior chamber, and a sampling chamber within the interior chamber for containing the specimen.

3. The cabinet x-ray system of claim 1 , wherein the specimen platform is configured for excised tissue, organ, or bone specimens.

4. The cabinet x-ray system of claim 1 , wherein the specimen platform is configured for any organic or inorganic specimen that fits inside the cabinet.

5. The cabinet x-ray system of claim 1 , wherein the specimen platform having a protective cover of and in physical contact with the x-ray detector.

6. The cabinet x-ray system of claim 1 , wherein the plurality of fixed x-ray sources includes at least three x-ray sources.

7. The cabinet x-ray system of claim 1 , wherein the plurality of fixed x-ray sources includes at least five x-ray sources.

8. The cabinet x-ray system of claim 1 , wherein the plurality of x-ray sources are positioned in a linear or arc-shaped arrangement.

9. A cabinet x-ray system for obtaining specimen x-ray images, projection x-ray images, and reconstructed tomosynthetic x-ray images of a specimen, the cabinet x-ray system comprising:

a cabinet defining an interior chamber;

a display;

an x-ray system including:

a flat panel x-ray detector;

a plurality of x-ray sources, wherein one of the plurality of x-ray sources is positioned at a standard imaging angle of approximately 0° relative to the flat panel x-ray detector; and

a specimen platform including a magnification tray that is positioned at a distance above the flat panel x-ray detector to facilitate geometric magnification imaging of the specimen in the cabinet; and

a controller configured to:

energize each of the plurality of x-ray sources separately to emit x-rays through the specimen to the flat panel x-ray detector such that an isocenter of the emitted x-rays of each of the plurality of x-ray sources is located at a surface of the flat panel x-ray detector;

control the flat panel x-ray detector to collect projection x-ray images of the specimen when each of the plurality of x-ray sources are separately energized to form a collection of x-ray images, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at the standard imaging angle of approximately 0°;

create a tomosynthetic x-ray image reconstructed from the collection of projection x-ray images;

process the collection of the projection x-ray images in the controller into one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively same or different from that of the two-dimensional x-ray image; and

selectively display the two-dimensional x-ray image and the one or more reconstructed tomosynthetic x-ray images.

10. The cabinet x-ray system of claim 9 , wherein the cabinet comprises a walled enclosure surrounding the interior chamber, a door configured to cover the interior chamber, and a sampling chamber within the interior chamber for containing the specimen.

11. The cabinet x-ray system of claim 9 , wherein the specimen platform is configured for excised tissue, organ, or bone specimens.

12. The cabinet x-ray system of claim 9 , wherein the specimen platform is configured for any organic or inorganic specimen that fits inside the cabinet.

13. The cabinet x-ray system of claim 9 , wherein the plurality of x-ray sources includes at least three x-ray sources.

14. The cabinet x-ray system of claim 9 , wherein the plurality of x-ray sources includes at least five x-ray sources.

15. The cabinet x-ray system of claim 9 , wherein the plurality of x-ray sources are positioned in a linear or arc-shaped arrangement in a range of from about 350° to about 10°, or front about 340° to about 20°, or a maximum of about 355° to 25°.

16. A method for obtaining and varying a superimposed image of an x-ray image and an optical image of a specimen in a cabinet x-ray and optical image system, wherein the cabinet x-ray and optical image system comprises:

a cabinet defining an interior chamber;

a display;

an x-ray system including:

an x-ray detector;

a plurality of fixed x-ray sources in an array, the plurality of fixed x-ray sources including fixed x-ray sources at end positions of the array, each fixed x-ray source of the fixed x-ray sources at the end positions of the array having a point source line of a beam such that an angle between point source lines of the fixed x-ray sources at the end positions of the array is from about 20° to about 50°, about 30°, or about 20°, wherein one of the plurality of fixed x-ray sources is positioned at a standard imaging angle of approximately 0° relative to the x-ray detector; and

a specimen platform; and

a controller configured to:

energize each of the plurality of fixed x-ray sources separately to emit x-rays through the specimen to the x-ray detector such that an isocenter of the emitted x-rays of each of the plurality of fixed x-ray sources is located at a surface of the x-ray detector;

control the x-ray detector to collect projection x-ray images of the specimen when each of the plurality of fixed x-ray sources are separately energized to form a collection of x-ray images, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at the standard imaging angle of approximately 0°;

create a tomosynthetic x-ray image reconstructed from the collection of projection x-ray images;

process the collection of the projection x-ray images in the controller into one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively same or different from that of the two-dimensional x-ray image; and

selectively display the two-dimensional x-ray image and the one or more reconstructed tomosynthetic x-ray images,

wherein the method comprises:

controlling the x-ray detector to collect projection x-ray images of the specimen when each of the plurality of x-ray sources are separately energized to form a collection of x-ray images, wherein one of the projection x-ray images is a two-dimensional x-ray image taken at a standard imaging angle of approximately 0°;

creating a tomosynthetic x-ray image reconstructed from the collection of projection x-ray images;

processing the collection of the projection x-ray images in the controller into one or more reconstructed tomosynthetic x-ray images representing a volume of the specimen and relating to one or more image planes that are selectively same or different from that of the two-dimensional x-ray image; and

selectively displaying the two-dimensional x-ray image and the one or more reconstructed tomosynthetic x-ray images.

17. The method of claim 16 , wherein the cabinet comprises a walled enclosure surrounding the interior chamber, a door configured to cover the interior chamber, and a sampling chamber within the interior chamber for containing the specimen.

18. The method of claim 16 , wherein the specimen platform is configured for excised tissue, organ, or bone specimens.

19. The method of claim 16 , wherein the specimen platform is configured for any organic or inorganic specimen that fits inside the cabinet.

20. The method of claim 16 , further comprising the specimen platform having a protective cover of and in physical contact with the x-ray detector.

Assignments (2)
CORRECTIVE ASSIGNMENT TO CORRECT THE SPELLING OF AN ASSIGNORS NAME PREVIOUSLY RECORDED ON REEL 051232 FRAME 0992. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT OF ASSIGNORS INTEREST. Recorded Jun 2, 2020
From: MANDALAPA-BHOOPATHY, VIGNESH
To: KUB TECHNOLOGIES, INC.
Reel/Frame 052816/0176 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 10, 2019
From: BUTANI, VIKRAM; CHEN, YAN; LOWE, CHESTER, DR.; MANDALA-BHOOPATHY, VIGNESH; MARIA-SELVARAJ, EDWIN; VELASCO, ROBERTO; YASUTAKE, PETER
To: KUB TECHNOLOGIES, INC.
Reel/Frame 051232/0992 →
Continuity (2)
Provisional Application 62777389 · Dec 10, 2018
Related Publication 20200182807A1 · Jun 11, 2020
Cited By (5)
US 12,324,690 US 12,364,443 US 12,396,693 US 12,514,523 US 12,714,383