Compounds and compositions for ossification and methods related thereto
The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.
1. A method of treating osteoporosis comprising administering an effective amount of 1-(4-chlorophenyl)-5-isopropyl-biguanide or salt thereof to a subject in need thereof.
2. The method of claim 1 wherein the subject is a human subject.
3. The method of claim 2 wherein the subject is diagnosed with osteoporosis.
4. A method of treating osteoporosis comprising administering an effective amount of 1-(4-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-1,3,5-triazine or salt thereof to a subject in need thereof.
5. The method of claim 1 wherein the subject is a human subject.
6. The method of claim 5 wherein the subject is diagnosed with osteoporosis.