Laser ablation catheters having expanded distal tip windows for efficient tissue ablation
Laser ablation catheters and methods of using same for efficient tissue ablation are disclosed. In some cases, laser ablation catheter embodiments may include expanded distal tips that allow for beam energy expansion and reduce dead space at the distal cutting surface of the laser ablation catheter.
1. A laser ablation catheter to ablate blockages in body lumens using high energy laser pulses, comprising:
a liquid filled waveguide including an elongate catheter body tube having an inner surface with a first index of refraction and a biocompatible ultraviolet transparent optical fluid disposed within and completely filling an inner lumen of the elongate catheter body tube, with the optical fluid having a second index of refraction which is greater than the first index of refraction; and
an ultraviolet grade elongated distal optical window disposed in liquid sealed relation to a surface of the elongate catheter body tube at a distal end of the elongate catheter body tube, the distal optical window including:
an insert segment which is disposed within a distal section of the elongate catheter body tube and which comprises an ultraviolet grade material,
a layer of material disposed about an outer surface of the insert segment which includes an index of refraction lower than an index of refraction of the material of the insert segment or a reflective material, and
an expanded segment which is disposed distally of the insert segment, which comprises an ultraviolet grade material configured to efficiently transmit ultraviolet optical energy for ablation of blockages in body lumens which has an outer diameter which is greater than an outer diameter of the insert segment, which has an output surface that has an area which is equal to or greater than an area of a transverse section of the elongate catheter body tube proximally adjacent the distal optical window and which has an axial length sufficient to allow optical energy expansion within the expanded segment such that optical energy emitted from the output surface ablates a hole in target tissue having a diameter equal to or greater than an outer diameter of the elongate catheter body tube proximally adjacent the distal optical window.
2. The laser ablation catheter of claim 1 wherein the insert segment comprises silica or sapphire.
3. The laser ablation catheter of claim 1 wherein the layer of material disposed about the outer surface of the insert segment comprises the inner layer of the catheter body tube.
4. The laser ablation catheter of claim 3 wherein the inner layer of the catheter body tube comprises an amorphous fluoropolymer.
5. The laser ablation catheter of claim 1 wherein the layer of material disposed about the outer surface of the insert segment comprises a material with an index of refraction lower than an index of refraction of the material of the insert segment and further comprises an amorphous fluoropolymer.
6. The laser ablation catheter of claim 1 wherein the layer of material disposed about the outer surface of the insert segment comprises a reflective material and further comprises a dielectric material or metal.
7. The laser ablation catheter of claim 1 wherein the expanded segment is not configured to act as a waveguide.
8. The laser ablation catheter of claim 1 further comprising an input optical window disposed in liquid sealed relation with a proximal end of the catheter body tube.