Tissue grasping devices and related methods
View Patent ↗A prosthetic device for sealing a native heart valves to prevent or reduce regurgitation comprises a spacer having one or more anchors. The spacer may also have atrial support structures, ventricular support structures, or both atrial and ventricular support structures In some cases, the spacer has anchors that attach to the leaflets as well as atrial and ventricular support. In some cases, the spacer straddles the annulus and is located by anchors, and in some cases the support structures can be implanted within the native heart valve. In some cases, the prosthetic device reduces the annulus diameter when implanted within the native heart vasculature. In some cases, the prosthetic device cinches the annulus when implanted within the native heart vasculature.
1. A prosthetic sealing device comprising:
a leaf-spring having a atrial leaf-spring segment and a ventricular leaf-spring segment, the segments being joined at a base and configured to open in response to an opening force to form to a leaflet-receiving gap and to resiliently close toward each other when the opening force is removed; and
a body attached to the base of the leaf-spring, wherein the body is configured to expand to inhibit the flow of blood through the body;
wherein the body comprises any one of (a) a hollowed shaft, wherein the shaft is flexible and/or foldable, (b) a sponge-like material that is compressible and flexible, (c) a gel-like material, and (d) a balloon connected to an inflator for remotely inflating the balloon to allow size adjustment after implantation.
2. A prosthetic sealing device comprising:
a leaf-spring having a atrial leaf-spring segment and a ventricular leaf-spring segment, the segments being joined at a base and configured to open in response to an opening force to form to a leaflet-receiving gap and to resiliently close toward each other when the opening force is removed; and
a body attached to the base of the leaf-spring, wherein the body is configured to expand to inhibit the flow of blood through the body;
wherein the body and the leaf springs are covered or coated with a material that promotes tissue in-growth.
3. The prosthetic sealing device of claim 2 , wherein the tissue in-growth promoting material comprises a polyester fabric.
4. The prosthetic sealing device of claim 1 , wherein the leaf-springs comprise atraumatic barbs to securely grasp leaflets.
5. The prosthetic sealing device of claim 1 , wherein the leaf-springs and body comprise a shape memory and/or super-elastic material.
6. The prosthetic sealing device of claim 5 , wherein the shape memory or super-elastic material comprises a nickel-titanium alloy.
7. A prosthetic sealing device comprising:
a leaf-spring having a atrial leaf-spring segment and a ventricular leaf-spring segment, the segments being joined at a base and configured to open in response to an opening force to form to a leaflet-receiving gap and to resiliently close toward each other when the opening force is removed;
a body attached to the base of the leaf-spring, wherein the body is configured to expand to inhibit the flow of blood through the body; and
a second set of leaf springs that are configured to secure both anterior and posterior leaflets, with the body attached in between or at a side of the leaf springs.
8. The prosthetic sealing device of claim 7 , further comprising a third set of leaf springs configured to secure each of the three tricuspid valve leaflets, with the body attached in between or at a side of the leaf-springs.
9. A prosthetic sealing device comprising:
a leaf-spring having a atrial leaf-spring segment and a ventricular leaf-spring segment, the segments being joined at a base and configured to open in response to an opening force to form to a leaflet-receiving gap and to resiliently close toward each other when the opening force is removed;
a body attached to the base of the leaf-spring, wherein the body is configured to expand to inhibit the flow of blood through the body; and
two or more sets of leaf springs that are configured to secure a single leaflet.
10. A prosthetic sealing device comprising:
a leaf-spring having a atrial leaf-spring segment and a ventricular leaf-spring segment, the segments being joined at a base and configured to open in response to an opening force to form to a leaflet-receiving gap and to resiliently close toward each other when the opening force is removed;
a body attached to the base of the leaf-spring, wherein the body is configured to expand to inhibit the flow of blood through the body; and
a retrieval feature configured to allow for retrieval of the prosthetic device during and/or after implantation.
11. The prosthetic sealing of device of claim 10 , wherein the prosthetic device is covered or coated with materials that inhibit formation of scar/fibrous tissue.