Stabilized hypohalous acid solutions
The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later use on demand. The invention further provides methods of making the stabilized hypohalous acid solution, as well as methods of use for disinfecting mammalian tissue, including wounds and burns, disinfecting or cleansing surfaces, or treating and/or preserving food products and cut flowers, among other uses.
1. A stabilized hypobromous acid (HOBr) solution consisting of:
a solution prepared by electrolysis of a solution consisting of water, a bromide salt, and optionally dissolved inorganic carbon (DIC) in the form of bicarbonate or carbonate of alkali or alkaline earth metals, and
a stabilizing amount of DIC in the form of bicarbonate or carbonate of alkali or alkaline earth metals, wherein an available free bromine (AFB) content of the solution is from about 10 to about 5,000 parts per million (ppm),
wherein the pH of the solution is from 4.0 to 7.5, and wherein a ratio of the stabilizing amount of the DIC to the AFB content is at least 1:2.
2. The solution of claim 1 , wherein the AFB content and the pH of the solution are stable for at least 6 months.
3. The solution of claim 1 , wherein the AFB content is from about 100 to about 1,000 ppm, from about 100 to about 500 ppm, or from about 150 to about 250 ppm.
4. The solution of claim 1 , wherein the pH is from 5.0 to 7.0.
5. The solution of claim 1 , wherein the pH is from 5.0 to 6.4.
6. The solution of claim 1 , wherein the DIC is sodium bicarbonate.
7. The solution of claim 1 , wherein the stabilized solution has an AFB content of from 100 ppm to 500 ppm and from 300 mg/L to 1000 mg/L of sodium bicarbonate.
8. A method for disinfecting or cleansing a mammalian tissue, comprising applying the solution of claim 1 to the mammalian tissue.
9. The method of claim 8 , wherein the mammalian tissue is infected, has a wound or a burn, has a dermatosis, or has atopic dermatitis.
10. A method for disinfecting or cleansing a hard surface, comprising applying the solution of claim 1 to the hard surface.
11. The method of claim 10 , wherein the hard surface comprises porcelain, steel, iron, or ceramic material.
12. A method for preserving or decontaminating food products, comprising applying the solution of claim 1 to a food product.
13. A method for controlling microbial contamination of water, comprising applying the solution of claim 1 to water in need of treatment or control for microbial contamination.