Lipid extraction processes
The present invention provides improved processes for extracting and preparing lipids from biological sources for use in pharmaceuticals, nutraceuticals and functional foods.
1. A composition comprising a solvent-extracted polar lipid-rich fraction from krill, said fraction comprising a protic solvent selected from the group consisting of n-butanol, n-propanol, isopropanol, ethanol, and methanol and a mixture of phospholipid compounds having the following structure:
wherein R1 and R2 are selected from the group consisting of a fatty acid moiety and —H and R3 is —H or a choline, ethanolamine, inositol or serine moiety,
wherein said mixture of phospholipid compounds comprises more than about 85% (mol %) choline moieties at position R3 and more than about 20% EPA and DHA combined at positions R1 and R2 and wherein the ratio of EPA:DHA is from 5:1 to 1:1, and
wherein said fraction comprises at least 50% phospholipids, and wherein said fraction is further characterized in having a conductivity of less than about 300 μS/cm measured in a saturated 60% ethanol solution.
2. The composition of claim 1 , wherein said fraction comprises at least 75% w/w of said phospholipid compounds.
3. The composition of claim 1 , wherein said fraction comprises at least 90% w/w of said phospholipid compounds.
4. The composition of claim 1 , wherein said fraction in said oral delivery capsule comprises at least 10% glyceride compounds comprising said omega-3 fatty acid moieties.
5. The composition of claim 1 , wherein said fraction comprises astaxanthin.
6. The composition of claim 5 , wherein said fraction has a astaxanthin monoester:astaxanthin diester ratio of greater than about 4:1.
7. The composition of claim 1 , wherein said fraction comprises less than about 0.05% w/w fatty acid esters.
8. The composition of claim 1 , wherein said fraction comprises less than 5% w/w lysophospholipids.